脑脉通胶囊稳定颈动脉易损斑块的临床研究

The Clinical Research of Naomaitong Capsule in Stabilizing Vulnerable Atherosclerotic Plaque of Carotid Artery

目的探讨脑脉通胶囊稳定颈动脉易损斑块和在缺血性卒中二级预防中的作用。方法对100例存在颈动脉易损斑块的缺血性卒中患者随机分为对照组和治疗组,对照组服用辛伐他汀片20 mg/次,每日1次,治疗组在对照组基础上给予脑脉通胶囊,观察1年后中医证候评分、颈动脉斑块积分、易损斑块和稳定斑个数、缺血性卒中事件的发生率。结果治疗组在中医证候评分、颈动脉斑块积分、易损斑块和稳定斑个数、缺血性卒中事件的发生率均优于对照组(P<0.05)。结论脑脉通胶囊能稳定颈动脉易损斑块,减少缺血性卒中事件的发生率。

Objective： To discuss the function of Naomaitong Capsule in stabilizing vulnerable atherosclerotic plaque of carotid artery and secondary prevention of ischaemic stroke. Methods： 100 patients were randomly di- vided in the control group and the treatment group. The control group took 20 mg of simvastatin tablet once per day. The treatment group took Naomaitong Capsule additionally. After 1 year,the following data was observed： TCM syndrome evaluation, calculus of carotid plaque,Vulnerable atherosclerotic plaque and the number of stable plaque,the incidence of ischaemic stroke. Results： the treatment group was better than the control group in TCM syndrome evaluation,calculus of carotid plaque,vulnerable atherosclerotic plaque and the number of stable plaque,the incidence of ischaemic stroke. Conclusion： Naomaitong Capsule can stabiliz vulnerable atherosclerot- ic plaque of carotid artery,reduce the incidence of ischaemic stroke.