中西医结合治疗卵巢早衰的诊治浅析

Progress of premature ovarian failure in diagnosis and treatment by integrative Chinese medicine and western medicine

卵巢早衰(premature ovarian failure,POF)是一种多病因所致的卵巢功能提前衰竭性疾病,至今发病机制尚未完全阐明。POF患者较正常年龄绝经妇女提前受到围绝经期症候群的困扰,出现持续性无排卵,卵巢、子宫、生殖道等性器官萎缩,导致性生活障碍、闭经、不孕症,影响家庭及社会稳定。POF病因复杂,诊治过程比较困难,随着科学与实验技术的日益提高,近年来国内外学者对卵巢功能衰竭的病因研究及中西医治疗有了很大进展。西医主要以激素替代治疗为主,随着基因治疗、干细胞移植、试管婴儿等技术的发展,为治疗卵巢早衰提供新的研究方向。中医以补肾宣郁、活血通经等治疗为主,从而恢复卵巢储备功能。

Premature ovarian failure（ POF） is a premature failure of ovarian function caused by many etiological factors,of which the pathogenesis has not been clarified so far. POF patients suffer from perimenopause earlier than healthy women and develop symptoms like ovarian atrophy,persistent amenorrhea and genital atrophy,and reproductive tract atrophy causing sexual disorders,anovulatory infertility,etc.,which affect the stability of family and society. Although the pathogenesis and treatment of POF are complicated and difficult,a great progress has been made by scholars on the study of the etiology of prematureovarian failure and the treatment with integrative Chinese medicine and western Medicine in recent years.