个体化低对比剂剂量注射方案在颈动脉计算机断层扫描血管造影中的应用

Application of individualized low-dose contrast medium injection scheme in carotid artery computed tomography angiography

目的探讨个体化低对比剂剂量注射方案在颈动脉计算机断层扫描(computed tomography,CT)血管造影(computed tomography angiography,CTA)中应用的可行性。方法对58例连续受检患者分为A、B两组行64层螺旋颈动脉CT成像,以4 m L/s速率进行高压团注,A组(29例)为低剂量对比剂组,对比剂总量(m L)为体质量(kg)×0.7;B组(29例)为对照组,对比剂总量(m L)为体质量(kg)×1.0。对患者体质量、对比剂剂量、各分支血管CT值及主观评分进行对比。结果A组对比剂剂量低于B组,差异有统计学意义[(41.82±6.78)m L vs.(61.72±9.12)m L,t=-9.426,P<0.05]。A组图像质量评分高于B组,差异有统计学意义(t=2.212,P=0.031)。结论个体化低对比剂剂量注射方案在颈部CTA中应用,能够满足甚至改善诊断的图像质量,能够运用于临床。

Objectives To explore the application feasibility of individual low-dose contrast medium injection scheme in carotid artery computed tomography（CT） angiography（CTA）. Methods Totally 58 patients by continuous examination were divided into group A and group B. They received 64-slice spiral CT imaging of carotid arteries at 4 m L / s for highpressure injection. Patients in group A（29 cases） received low-dose contrast medium, the volume（m L） equaled to the weight（kg） ×0.7; Patients in group B（29 cases） were controls, the contrast medium volume（m L） equaled to the weight（kg） ×1.0. Patients＇ weight, contrast medium dose, CT value of each branch vessel and subjective score were compared between the two groups. Results Contrast medium dose of A group was significantly lower than that of B group [（41.82 ±6.78） m L vs.（61.72 ±9.12） m L, t =-9.426, P〈0.05 ]. Image quality score of A group was obviously higher than that of B group（t =2.212,P =0.031）. Conclusions Individualized low-dose contrast medium injection scheme in CTA of carotid arteries can satisfy the image quality requirements and even improve the diagnostic image quality, thus it can be applied in clinical practice.