冠状动脉侧支循环对左心室重构的影响

Effect of coronary artery collateral circulation on left ventricular remodeling

目的分析冠状动脉粥样硬化性心脏病(冠心病)患者冠状动脉造影侧支循环对左心室重构的影响。方法回顾性分析410例在广州市第一人民医院心内科行选择性冠状动脉造影术(CAG)的患者的临床资料,入选患者行冠状动脉造影及超声心动图检查及抽静脉血标测血生化指标。患者按冠状动脉造影结果分为冠心病组和对照组;冠心病组按Rentrop's分级法分为Rentrop's 0、1、2、3亚组。比较各组基线资料和心室重构指标。结果冠心病组和对照组及各亚组间基线资料比较,差异无统计学意义(P>0.05)。Rentrop's 0、1、2、3组左心室质量指数比对照组高,差异有统计学意义(P<0.05);Rentrop's 0、1、2、3亚组各组间左心室质量指数比较,差异有统计学意义(P<0.05)。结论侧支循环能够改善心室重构。

Objectives To analyze the effect of coronary artery collateral circulation on left ventricular remodeling in patients with coronary heart disease. Methods Clinical data of 410 cases who received selective coronary angiography（CAG） in The First People＇s Hospital of Guangzhou were retrospectively analyzed. CAG and echocardiography were performed and biochemical indicators of blood were measured in all the patients. According to the results of CAG, the patients were divided into coronary heart disease group and control group. According to the Rentrop classification scheme, the patients in coronary heart disease group were further divided into Rentrop 0, 1, 2, 3 subgroups. Baseline data and indexes for left ventricular remodeling were compared between the two groups and among the subgroups.Results Baseline data between coronary heart disease group and control group, among Rentrop 0, 1, 2, 3subgroups had no significant difference（P〉0.05）. Left ventricular mass indexes（LVMI） in Rentrop 0, 1, 2, 3subgroups were obviously higher than that in control group（P〈0.05）, and LVMI had significant differences among Rentrop 0, 1, 2,3 subgroups（P〈0.05）. Conclusions Collateral circulation can improve ventricular remodeling.