疏肝健脾化痰汤治疗非酒精性脂肪性肝炎50例

Shu Gan Jian Pi Hua Tan Tang in Treating 50 Patients with Non-alcoholic Steatohepatitis

目的:观察疏肝健脾化痰汤治疗非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)的临床疗效。方法:将100例NASH患者随机分为对照组、治疗组各50例,对照组口服护肝降酶和降血脂西药,治疗组在对照组基础上给予疏肝健脾化痰汤。观察对比治疗前及治疗后12、24、36、48周彩色多普勒肝脏超声声像图的变化。结果:总有效率对照组为72.0%,治疗组为96.0%。治疗组优于对照组(P<0.05)。治疗后2组肝脏超声回声衰减程度明显减轻(P<0.05),观察组减轻更明显(P<0.05)。结论:疏肝健脾化痰汤治疗NASH临床疗效较好。

Objective： To observe clinical effects of ShuGan JianPi HuaTan Tang in treating non-alcoholic steatohepatitis （NASH）. Methods： One hundred patients were randomized into the control group and the treatment group, the control group took drugs to protect liver, decreasing enzyme and blood lipid, and treatment group took ShuGan JianPi HuaTan Tang on the foundation of the therapy the control group received. The changes of Color Doppler liver ultrasonography were observed and compared before treating, in 12, 24, 36, 48 weeks after treating. Results： Total effective rate of the control group was 72.0%, lower than 96.0% of the treatment group（P〈0.05）. After treating, liver ultrasonic echo attenuation degrees in both groups alleviated slightly（P〈0.05）, the decrease of the treatment group was more obvious（P〈0.05）. Conclusion： ShuGan JianPi HuaTan Tang is effective in treating NASH.