NT-proBNP对慢性阻塞性肺疾病急性加重期患者预后的预测价值被引量：7

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摘要目的研究N-末端脑钠肽前体(NT-pro BNP)水平及社区获得性肺炎评分(CURB-65评分)与慢性阻塞性肺疾病急性加重期(AECOPD)患者预后的关系。方法 215例AECOPD患者入院时进行CURB-65评分及NTpro BNP测定,所有患者随访临床结局(存活和死亡),比较不同CURB-65评分和不同NT-pro BNP水平患者的预后差异,评价NT-pro BNP水平与不同CURB-65评分患者预后的关系。结果 CURB-65评分高危组患者病死率明显高于CURB-65评分中低危组(P<0.01),NT-pro BNP水平升高与病死率明显相关(P<0.01)。在CURB-65评分高危组及中低危组中,NT-pro BNP升高均与患者病死率明显相关(P均<0.05)。结论 NT-pro BNP水平升高及CURB-65评分高危均提示AECOPD患者近期预后不良,NT-pro BNP升高对不同CURB-65评分患者均有预后预测价值。

作者刘威威胡波殷青陈晓香王帅兵

机构地区河北省廊坊市人民医院中国石油中心医院

出处《现代中西医结合杂志》 CAS 2015年第21期2318-2319,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine

基金廊坊市科技计划项目(2013013007)

关键词慢性阻塞性肺疾病急性加重期 CURB-65评分 NT-pro BNP 预后

分类号 R563 [医药卫生—呼吸系统]

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