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血小板参数的变化对于判断溃疡性结肠炎活动情况的临床意义

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摘要 回顾性分析本院UC活动期患者38例,缓解期35例,按临床表现分轻、中、重度三组。治疗前后分别空腹抽取静脉血,分别检测血小板计数(PLT)及血小板平均体积(MPV)、血C反应蛋白(CRP)。组内比较采用单因素方差分析,两两比较用非参数检验;PLT、MPV、CRP采用Spearmman等级相关性分析。结果⑴CRP、PLT值在活动期UC患者高于缓解期(P<0.01),MPV低于缓解期(P<0.05)。⑵在活动期UC患者中,UC重度患者PLT、CRP高于轻度患者,MPV低于轻度患者,差异具有统计学意义;UC中度与重度比较,只有PLT具统计学差异(P<0.01)。⑶Spearmman等级相关性分析表明,UC活动期患者PLT与CRP变化存在正相关性(r=0.580,P<0.01);MPV与CRP变化存在负相关性(r=0.502,P<0.01)。综合考虑CRP、PLT及MPV的变化能够反映UC的活动性,且PLT、MPV和CRP在临床中很容易检测,可以作为评价的客观指标之一,对于病情的判断有很好的临床指导作用。
作者 郑奕 张启芳
出处 《现代诊断与治疗》 CAS 2015年第6期1303-1305,共3页 Modern Diagnosis and Treatment
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