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细胞命运决定因子1(DACH1)在恶性肿瘤中的作用和机制 被引量：2

Roles of Dachshund homologue 1(DACH1)in growth of malignant tumors and their mechanisms
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摘要 该文综述细胞命运决定因子(DACH1)的来源、结构、功能和在恶性肿瘤中的作用及其调控肿瘤生长的机制,为今后探讨以DACH1为靶标的肿瘤靶向诊断和辅助治疗提供依据。 This paper reviews the source,structure and function of the cell fate determination factor 1（Dachshund homologue 1,DACH1）,and roles in growth of malignant tumors and their regulation mechanisms,in order to explore DACH1 as a target for targeting diagnosis and adjuvant therapy of malignant tumors.
作者 曹进 范跃祖
机构地区 同济大学医学院 同济大学附属同济医院普外科
出处 《外科研究与新技术》 2015年第1期44-47,共4页 Surgical Research and New Technique
关键词 细胞命运决定因子1 肿瘤 作用机制 Dachshund homologue 1 Neoplasm Effect mechanism
分类号 R730 [医药卫生—肿瘤]
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  • 4Popov VM,Zhou J,Shirley LA. The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling[J].Cancer Research,2009,(14):5752-5760.
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  • 9Lee JW,Kim HS,Kim S. DACH1 regulates cell cycle progression of myeloid cells through the control of cyclin D,Cdk 4/6 and p21(Cip1)[J].Biochemical and Biophysical Research Communications,2012,(01):91-95.
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外科研究与新技术
2015年 第1期

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