华枝睾吸虫感染与胆道结石术后并发症的关系

Relationship Between Clonorchis Sinensis Infection and Postoperative Complications of Patients with Biliary Calculi

目的探讨华枝睾吸虫(肝吸虫)感染与胆道结石术后并发症的关系。方法将手术治疗的胆道结石患者263例,按是否合并肝吸虫感染分为感染组(90例)和非感染组(173例),感染组均接受规范驱虫治疗。观察两组病人术后并发症的发生情况。结果感染组发生术后胆漏7例,胆汁淤积2例,胆管结石复发1例,非感染组分别为4例、1例、1例。感染组术后第1天、第5天的胆汁引流量显著多于对照组(P<0.05),第9天两组无统计学差异(P>0.05)。感染组平均住院时间显著长于非感染组(P<0.05)。结论合并肝吸虫感染的胆道结石患者术后更易发生相关并发症,驱虫治疗可以有效避免术后并发症。

Objective To study the relationship between clonorchis sinensis（liver fluke） infection and postoperative complications of patients with biliary calculi. Methods 263 cases of biliary calculi patients with surgical treatment were divided into infection group（n = 90）and non-infection group（n = 173） depending on liver fluke infection situation. Patients with liver fluke infection were given standardized worm-expelling treatment. The postoperative complications were observed. Results After surgery, the number of case of bile leakage,cholestasis and recurrence of bile duct stone were 7, 2 and 1 in infection group, and 4, 1 and 1 in non-infection group. The bile drainage volume of infection group was more than that of non-infection group at 1stday and 5thday after surgery（P 0.05）, but no statistical difference was found at 9thday after surgery（P 0.05）. The average length of hospital stay of infection group was significantly longer than that of non-infection group（P 0.05）. Conclusions Biliary calculi patients complicated with liver fluke infection are more likely to happen related complications, and worm-expelling treatment can effectively avoid complications.