钠离子结合康妇消炎栓治疗慢性盆腔炎的疗效观察

Efficacy of Sodion Combined with Kangfuxiaoyan Suppository for the Treatment of Chronic Pelvic Inflammatory Disease

目的探讨钠离子结合康妇消炎栓治疗慢性盆腔炎(CPID)的临床疗效。方法选取慢性盆腔炎患者300例,随机分为两组各150例,对照组单用康妇消炎栓治疗,观察组给予康妇消炎栓联合钠离子治疗。观察两组治疗后血清CRP、TNF-α及IL-6水平,比较两组临床疗效、不良反应以及复发率。结果两组患者治疗后血清CRP、TNF-α及IL-6水平均显著下降,差异有统计学意义(P<0.05)。2个疗程后观察组治愈率58.67%,总有效率93.33%,均显著高于对照组的32.00%、74.67%(P<0.05)。随访期间观察组复发率为9.09%(8/88),显著低于对照组的75.00%(36/48),P<0.05。结论钠离子结合康妇消炎栓治疗慢性盆腔炎,疗效显著,值得临床推广应用。

Objective To explore the clinical effect of sodion combined with Kangfuxiaoyan suppository for the treatment of chronic pelvic inflammatory disease（CPID）. Methods 300 patients with CPID were randomly divided into two groups equally. The control group was treated with Kangfuxiaoyan suppository, while the observation group was treated with sodion combined with Kangfuxiaoyan suppository. The serum CRP, TNF-α and IL-6 levels before and after treatment were observed, and the clinical effects, adverse reactions, and recurrence rate were compared between two groups. Results After treatment, the serum CPR, TNF-α and IL-6 levels decreased significantly（P 0.05）. After two courses of treatment, the cure rate and total effective rate of observation group were 58.67% and 93.33% respectively,significantly higher than 32.00% and 74.67% of control group, respectively（P 0.05）. During follow-up, 8 cases（9.09%） had recurrence,significantly fewer than 36 cases（75.00%） of control group（P 0.05）. Conclusions The clinical efficacy of sodion combined with Kangfuxiaoyan suppository for the treatment of CPID is significant.