五味消毒饮合枇杷清肺饮治疗肺经风热型痤疮120例临床观察

Clinical Observation on Treatment of Acne Due to the Lung by Wind and Heat with Pipaqingfei and Wuweixiaodu Drinks

[目的]观察五味消毒饮合枇杷清肺饮治疗肺经风热型痤疮的疗效。[方法]浙江省中医院皮肤科门诊120例患者,采用随机数表法分为治疗组60例和对照组60例。治疗组给予五味消毒饮合枇杷清肺饮煎剂,1剂/d,水煎服;对照组给予丹参酮胶囊口服,4粒/次,4次/d。每组都以4周为1个疗程。[结果]1个疗程后,治疗组总有效率达到86.67%,对照组的有效率58.33%,两者相比差异具有统计学意义(P<0.01)。治疗前后的两组皮损评分比较,Ⅰ级与Ⅱ级痤疮的治疗组治疗后评分相比,差异具有统计学意义(P<0.05),Ⅲ级与Ⅳ级痤疮的治疗组评分相比,差异具有统计学意义(P<0.01)。[结论]五味消毒饮合枇杷清肺饮能显著改善肺经风热型痤疮患者的皮损情况及风热证候,临床疗效确切,不良反应轻,且对重度痤疮患者治疗效果更优。

Objective] To investigate Wuweixiaodu drinks combined Pipaqingfei drinks curative effect for the treatment of acne due to the lung by wind and heat.[Methods] 120 patients from Hospital of Zhejiang Province Dermatologists,using a random number table divided into treatment group of 60 patients and a control group of 60 patients.The treatment group received Wuweixiaodu drinks together with Pipaqingfei drinks,one day one decoction; control group was given Danshentong capsules orally,4 pills,4 times a day.Each set to four weeks for a course of treatment.[Results] After a course of treatment, the rate of basic recovery from treatment group was 86.67%,and the control group was 58.33%,having a significant difference（P〈0.05）.Lesions scores after treatment between the two groups,the scores of gradeⅠ,Ⅱacne treatment group had statistically significant difference（P〈0.05） after treatment,the scores of grade Ⅲ, Ⅳ acne treatment group had a very significant difference（P〈0.01） after treatment.[Conclusion] Wuweixiaodu drinks with Feijingfengre drinks is effective to acne due to the lung by wind and heat,therapeutic effect for severe acne is better and has less adverse reactions.