促排卵颗粒对排卵障碍性不孕症促排卵疗效观察

Clinical Effects of Cupailuan Granule in treating Ovulation Failure Infertility

目的:观察促排卵颗粒治疗排卵障碍性不孕症的临床疗效。方法:将95例患者按随机数字表法分为治疗组和对照组,治疗组(48例)服用促排卵颗粒,对照组(47例)服用克罗米芬,B超监测卵泡发育和排卵状况、子宫内膜生长情况,观察基础体温、妊娠情况。结果:治疗组和对照组排卵率分别为70.83%、76.60%,2组比较差异无统计学意义;而治疗组妊娠率50.00%,对照组29.87%,2组比较差异有统计学意义;2组治疗后优势卵泡直径较治疗前差异有统计学意义,组间比较差异无统计学意义。治疗组子宫内膜厚度显著增长且优于对照组。结论:促排卵颗粒可促进卵泡发育、排卵及子宫内膜增长,提高妊娠率,对排卵障碍性不孕症有较好疗效。

Objective： To observe the clinical effect of Cupailuan Granule in treating ovulation failure infertility.Method： Ninety-five patients were randomly divided into two groups： the treatment group（ 48 cases） and the control group（ 47 cases）. The treatment group was given the Cupailuan Granule,whereas the control group was given clomiphene citrate.Ultrasound examinations were used to monitor the development of follicles,ovulation and endometrium and to observe basal body temperature,pregnancy. Resutts： The ovulation rate of treatment and control groups are 70. 83 % and 76. 60%respectively. There were no significant differences between the two group. However,the pregnancy rate of the treatment group was 50. 00% while that of the control group was 29. 97%. The size of follicles and the thickness of the endometrium were significantly improved after treatment in the treatment group. Conclusion： Cupailuan Granule is effective in treating ovulation failure infertility and can increase the pregnancy rate greatly.