瑞芬太尼复合七氟醚在新生儿全身麻醉中的应用

Application of remifentanil combined with sevoflurane anesthesia in neonates during general anesthesia

目的：探讨临床对新生儿采取瑞芬太尼及七氟醚复合全身麻醉的效果．方法：将2013-01／2015-01到我院行全身麻醉治手术疗的60例新生儿纳入研究，并通过随机对照法等分成两组，两组均通过七氟醚诱导，其中对照组30例单纯予七氟醚维持麻醉，观察组30例选择瑞芬太尼与七氟醚进行复合麻醉，记录两组对象不同时间点的HR、MAP指标变化情况，以及其拔管和苏醒时间．结果：两组T0、T1时点的HR与MAP指标值基本相仿，不具统计学意义（P〉0．05），但观察组T2-T3时点的HR、12时点的MAP值相比对照组明显更低，有统计学意义（P〈0．05）．结论：对新生儿采取瑞芬太尼及七氟醚复合进行全身麻醉，麻醉效果较理想，且可促进患儿术后苏醒，可控性更佳，适合推广．

AIM： To investigate the clinical by remifentanil and sevoflurane anesthesia effect of newborn. METHODS： 60 cases of neonatal anesthesia for surgical treatment were enrolled in the study in our hospital January 2013 to January 2015, and through the randomized divided into two groups, the two groups were all induced by sevoflurane, and the 30 cases in the control group were treated by sevoflurane only, but the observation group of 30 cases were treated by remifentanil and sevoflurane anesthesia to- getther. HR and MAP index of the records of two groups at different time points, and the extubation time and analepsia time. RE- SULTS： The HR and MAP index of the two groups of TO, T1 point values were not statistically significant （P 〉 0.05 ）, but the observation group at T2 - T3, HR, T2 at MAP values were signif- icantly lower compared with the control group, there was statistical significance （ P 〈 0. 05 ）. CONCLUSION： Remifeutanil and sevoflurane take general anesthesia for neonatal, anesthesia effect is ideal, and can promote the postoperative recovery, better controllability, suitable for promotion.