丙泊酚在重型颅脑损伤并脑疝形成患者急症手术的麻醉分析

Analysis of propofol in emergency operation anesthesia of patients with severe craniocerebral injury and cerebral hernia formation

目的:探索丙泊酚在重型颅脑损伤并脑疝形成患者急症手术的麻醉效果,为临床的研究提供一定的理论依据.方法:选择在我院进行治疗的重型颅脑损伤并脑疝形成的患者36例作为研究对象,将其随机分为实验组和对照组.在手术过程中,实验组采用丙泊酚联合芬太尼进行麻醉,对照组采用异氟醚进行麻醉,观察比较这两组患者的生命体征和麻醉效果.结果:两组患者均无麻醉死亡病例,无明显不良反应,各项生命体征平稳.实验组的患者恶心呕吐率比对照组明显降低,且两组患者间的差异具有统计学意义(P<0.05).结论:丙泊酚在重型颅脑损伤并脑疝形成患者急症手术的麻醉效果明显,且患者无明显不良反应,值得在临床上推广.

AIM： To explore the anesthetic effect of propofol on patients with severe traumatic brain injury and brain herniation during emergency operation, and provide a theoretical basis to clinical research. METHODS： A total of 36 patients with severe craniocerebral injury and cerebral hernia formation admitted to our hospital were selected as the research objects and were randomly divided into observation group and control group. During the operation, the experimental group used propofol combined with fenta- nyl for anesthesia, while the control group received isoflurane anesthesia. The vital signs and anesthetic effect were then observed and compared between the two groups. RESULTS： For the two groups, there was no death case, no significant adverse reactions, and the life signs were stable. Patients with nausea and vomiting of the experimental group were significantly less than that of the control group, and the difference was statistically significant （P 〈 0.05 ）. CONCLUSION： During emergency operation, the anesthetic effect of propofolin on patients with severe craniocerebral injury and cerebral hernia formation was obvious, causes no obvious adverse reactions, and is worthy of promoting in clinical.