苓蔻人参汤结合艾灸治疗慢性溃疡性结肠炎69例疗效观察

Efficacy of Lingkou Renshen decoction combined with moxibustion in treatment of chronic ulcerative colitis: a report of 69 cases

目的:观察苓蔻人参汤结合艾灸治疗慢性溃疡性结肠炎的临床疗效。方法:将136例慢性溃疡性结肠炎患者随机分成两组,治疗组69例采用苓蔻人参汤结合艾灸治疗,对照组67例采用柳氮磺吡啶结肠溶胶囊治疗。连续治疗6周。观察治疗前后腹泻、脓血便、腹痛和肠镜变化。6个月后比较两组复发率。结果:总有效率治疗组为85.5%,对照组为73.1%,组间比较,差异有统计学意义(P<0.05);腹泻、脓血便、腹痛、肠镜的改善治疗组优于对照组(P<0.05);复发率治疗组明显低于对照组(P<0.05)。结论:苓蔻人参汤结合艾灸治疗慢性溃疡性结肠炎临床疗效较好,值得临床推广运用。

Objective ： To observe the clinical efficacy of Lingkou Renshen decoction combined with moxibustion in the treatment of chronic ulcerative colitis. Methods： A total of 136 patients with chronic ulcerative colitis were randomly divided into treatment group （ n = 69 ） and control group （ n = 67 ）. The treatment group received Lingkou Renshen decoction combined with moxibustion, while the control group received sulfasalazine colonosoluble cap- sules. Both groups received treatment for six weeks. The improvements in diarrhea, stool with blood and pus, abdomi- nal pain, and enteroscopic findings after treatment were evaluated. The recurrence rate was compared between the two groups six months later. Results：The treatment group had a significantly higher overall response rate than the control group （ 85.5 % vs73.1% , P 〈 0. 05 ）. Compared with the control group, the treatment group had significantly more improvements in diarrhea, stool with blood and pus, abdominal pain, and enteroscopic findings （ P 〈 0. 05 ）. The recurrence rate was significantly lower in the treatment group than in the control group （ P 〈 0. 05 ）. Conclusion ： Lingkou Renshen decoction combined with moxibustion has good clinical efficacy in the treatment of chronic ulcerative colitis and holds promise for clinical application.