兰州市动物实验研究人员对ARRIVE指南及GSPC知晓情况调查

A Survey on Awareness of the ARRIVE Guideline and GSPC in Researchers Field in Animal Experiments Field in Lanzhou City

目的了解动物实验研究报告指南(ARRIVE指南)与动物实验金标准报告清单(GSPC)在兰州市动物实验研究相关人员中的知晓情况,为其有效推广提供参考依据。方法采用自行设计的问卷对兰州市医学院校教师和临床医学研究生进行调查。调查内容包括调查对象的基本信息,对ARRIVE指南、GSPC及其他医学研究报告指南的知晓情况等。采用SPSS 21.0软件进行统计分析。结果共发放调查问卷329份(包括40名教师和289名研究生),最终回收有效答卷287份。调查结果显示:ARRIVE指南和GSPC在兰州市医学院校教师和研究生中的知晓率,分别为12.5%和11.8%,且师生间知晓率无明显差异(P=0.903)。调查途径以及调查对象的年龄、学历、职业、单位均对知晓率无明显影响(P均>0.05)。调查对象知晓报告指南的主要途径为网络(33.4%)、相关论文(21.2%)和学术报告(17.4%)。结论 ARRIVE指南与GSPC在兰州市动物实验相关人员中的知晓率较低,需要采取针对性措施进行推广与普及。

Objective To investigate the awareness situation on the ARRIVE guideline and the Gold Standard Publication Checklist （GSPC） of animal experiments in researchers in animal experiments field in Lanzhou city, in order to improve the promotion of the two reporting guidelines in China. Methods A self-designed questionnaire was used to investigate the clinical graduate students and teachers in medical college in Lanzhou city, The investigation contents mainly included the basic information of the respondents, the awareness situation on the ARRIVE guideline, GSPC and other medical reporting guidelines. SPSS 21.0 software was used for data analysis. Results A total of 329 questionnaires （40 were from teachers and 289 were from graduate students） were issued, of which, 287 questionnaires were effective, The results showed that the awareness rate on the ARRIVE guideline and GSPC in clinical graduate students and teachers in medical college in Lanzhou city were 11,8% and 12.5%, respectively, and there was no significant difference between students and teachers in awareness rate （P=0.903）. The survey approaches, the age, education, job, and the organization of the respondents were all not the influence factors of awareness rate （P〉0.05）. The respondents knew about the reporting guidelines mainly through the website （33.4%）, related studies （22.2%） and academic reports （17.4%）. Condusion The awareness rate on the ARRIVE guideline and GSPC is relative low in researchers in animal experiments field in Lanzhou city, and it needed to take purposeful measures to promote and popularize them.