小儿肺炎继发性腹泻相关因素分析及微生态制剂的预防作用

Analysis of related factors and prevention effect by microecologics for pediatric pneumonia secondary diarrhea

目的研究小儿肺炎继发性腹泻的相关因素及微生态制剂的预防作用。方法 227例肺炎患儿随机分为预防组(113例)和非预防组(114例),预防组患儿住院后给予抗菌药物与微生态制剂[枯草杆菌二连活菌颗粒(妈咪爱)],非预防组在患儿腹泻出现后才加用妈咪爱。应用单因素分析,Logistic多因素回归分析危险因素和保护性因素。结果两组发生继发性腹泻例数比较差异有统计学意义(P<0.05)。Logistic多因素回归分析显示,年龄、住院时间、抗菌药物联合应用为小儿肺炎继发性腹泻的危险因素,微生态制剂预防性应用为保护性因素。结论年龄小、住院时间长以及抗菌药物联合应用会增加肺炎患儿继发性腹泻发生的危险性,微生态制剂预防性使用可以降低其发生率。

Objective To research related factors and prevention effect by microecologics for pediatric pneumonia secondary diarrhea. Methods A total of 227 children with pneumonia were randomly divided into prevention group （113 cases） and non-prevention group （114 cases）. The prevention group received antibacterial agents and microeeologics after admission [bacillus subtilis double living bacterium particles （medilac-vita）], and the non-prevention group received medilac-vita after diarrhea. Risk factors and protective factors were analyzed by univariate and multivariate Logistic regression analysis. Results The difference of secondary diarrhea eases between the two groups had statistical significance （P〈0.05）. Multivariate Logistic regression analysis showed that age, hospital stay, and combination of antibacterial agents were the risk factors of pediatric pneumonia secondary diarrhea. Preventive application of microecologics provided the protective factor. Conclusion Young age, long hospital stay, and combination of antibacterial agents will increase the risk in occurrence of secondary diarrhea in pneumonia children. Prevention application of microecologics can reduce its incidence.