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动物视觉功能检测的研究进展及其在动物视觉功能研究中的应用 被引量:2

Progress on animal visual function testing and its application in visual function study
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摘要 视觉是人类获取外界信息的主要通道,对人类的生活、工作有重要的意义。预防视觉系统下降(或损伤)、消除可避免的眼盲是眼科领域的主要任务和我国人类健康的奋斗目标之一。视觉功能的改善或恢复是视觉系统疾病临床治疗的最重要指标,因此视觉功能检查在眼科有特殊的意义。而人类疾病动物模型是基础研究向临床转化的关键环节, Human obtain the outside information mainly from the visual system which is important in human work and life. To improve or recover visual function is the most important indicator in clinical treatment,and visual function testing has special meaning in ophthalmology. The animal models are the key transformation from basic research to clinical outcome. Visual function testing in laboratory animals is also a very important indicator in animal study. For example,psychophysical methods are the main means to check human vision function,but not suitable for animals. Therefore,it needs to focus on research of visual function in animals and application of visual function testing in laboratory animals.
作者 张作明
出处 《第三军医大学学报》 CAS CSCD 北大核心 2015年第12期1171-1173,共3页 Journal of Third Military Medical University
基金 国家"十二五"重大新药创制项目(2011ZX09301-001)~~
关键词 视觉功能 动物模型 视觉功能检测 visual function animal model visual function testing
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  • 1顾永昊,张作明,侯豹可,郭群,李莉,龙潭.明适应过程中SD大鼠视锥细胞反应的变化规律[J].第四军医大学学报,2003,24(19):1777-1779. 被引量:2
  • 2彭晓燕,王光璐,焦树玲,严伟.玻璃体内注入庆大霉素致视网膜中毒性改变[J].中华眼底病杂志,1996,12(2):134-135. 被引量:10
  • 3叶洪金 李培忠 刘晓明.不同年龄大鼠的视网膜电图[J].中华老年医学杂志,1993,12(6):354-355.
  • 4Editorial. Mouse megascience. Nature, 2010, 465(7298): 526.
  • 5Abbott A. Mouse project to find each gene's role. Nature, 2010, 465(7297): 410-1.
  • 6Niu YY, Yu Y, Bemat A, et al. Transgenic rhesus monkeys produced by gene transfer into early-cleavage-stage embryos using a simian immunodeficiency virus-based vector. Proc Natl Acad Sci USA. 2010. 107(41): 17663-7.
  • 7Teng Y, Xie X, Walker S, et al. Knockdown of zebrafish Lgi 1 a results in abnormal development, brain defects and a seizure-like behavioral phenotype. Hum Mol Genet, 2010, 19(22): 4409-20.
  • 8Nicoli S, Ribatti D, Cotelli F, et al. Mammalian tumor xenografts induce neovascularization in zebrafish embryos. Cancer Res, 2007, 67:2927-31.
  • 9Lee G, Papapetrou EP, Kim H, et al. Modelling pathogenesis and treatment of familial dysautonomia using patient- specific iPSCs. Nature, 2009, 461(7262): 402-6.
  • 10Alberts B. Model organisms and human health. Science, 2010, 330:1724.

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