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症状前期帕金森病的PET/SPECT功能影像学研究 被引量：2

PET/SPECT Functional Imaging Study of Parkinson's Disease in Pre-motor Stage
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摘要 帕金森病(PD)是一种慢性中枢神经系统退化性病变。目前有充分的证据显示PD的特征性病理学改变在临床起病之前即可出现,即在所谓症状前期的亚临床阶段。以PET/SPECT为代表的功能影像学技术已在临床PD诊断中得到广泛应用,通过对PD患者黑质纹状体多巴胺能功能的评估,可客观、有效地对PD进行诊断及鉴别诊断。文中就PET/SPECT功能影像学技术在检测症状前期PD中的应用作一综述。 Parkinson’s disease （PD） is a chronic progressive disease of the central nerve system. There are evidence showed that characteristic changes in pathology can appear before clinical symptoms in so-called pre-motor stage. Functional imaging techniques as PET/SPECT have been wildly used in diagnosis of PD, mainly targeting the dopamine function in nigrostriatal system. The application of PET/SPECT in diagnosis of PD in the pre-motor stage was reviewed.
作者 黄喆慜 左传涛 武猛
机构地区 复旦大学附属华山医院PET 海军青岛江西路干休所卫生所
出处 《中国临床神经科学》 2015年第3期355-358,共4页 Chinese Journal of Clinical Neurosciences
关键词 帕金森病 功能影像学 正电子发射断层显像 单光子发射断层显像 症状前期 Parkinson’s disease functional imaging positron emission tomography SPECT pre-motor stage
分类号 R742.5 [医药卫生—神经病学与精神病学] R817 [医药卫生—影像医学与核医学]
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参考文献17

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中国临床神经科学
2015年 第3期

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