耳穴压豆联合遮盖法及中药治疗儿童弱视的随机对照临床研究

Randomized Controlled Clinical Trials for Treatment of Child Amblyopia with Otopoint Pelletpressure Combined with Chinese Medical Herbs

目的:观察耳穴压豆联合遮盖法及中药治疗儿童弱视的临床疗效。方法:将66例弱视患儿按照随机数字表法随机分为对照组及治疗组,每组33例,分别为47和45只眼。对照组给予遮盖法及辨证加服中药治疗,治疗组在此基础上在双侧耳穴眼、肝、肾、心、目1、目2、脾穴加用耳穴压豆疗法,疗程均为6个月。观察患者临床疗效、视力变化情况、视力改善起效时间以及随访3个月和6个月复发率。结果:治疗组总有效率为75.56%(34/45),明显高于对照组的42.55%(20/47,P<0.05);治疗组视力变化情况明显优于对照组(P<0.05);治疗组2周起效人数明显高于对照组(P<0.05);治疗组3个月及6个月复发率均低于对照组(P<0.05)。结论:耳穴压豆联合遮盖法及中药治疗弱视有效率高、起效快、视力改善明显、复发率低。

Objective To observe the clinical effect of auricular pressure combined with Chinese herbal medicine for amblyopia.Methods A total of 66 child patients with amblyopia were randomly divided into Chinese herbal medicine（control）and herbal medicine＋auricular pressure（treatment）groups,with 33 patients in each group.The patients in the control group were treated with Chinese medical herbs as Danggui（RadixAngelicae Sinensis）,Gouqizi（Fructus Lycii）,Baijuhua（Flos Chrysanthemi）,Baizhu（Rhizoma Atractylodis Macrocephalae）,Shudi（Radix Rehmanniae Praeparata）,Baishao（Radix Paeoniae Alba）,etc.according to syndrome differentiation,while the patients in the treatment group were treated by auricular pressure of otopoints Yan（Eye）,Gan（Liver）,Shen（Kidney）,Xin（Heart）,Mu 1（Eye-1）,Mu 2（Eye-2）,and Pi（Spleen）and herbal medicines（being the same to the control group）.The treatment was conducted for 6months.After the treatment,the clinical effect,improvement degree of vision,onset time of improvement,and recurrence rate in the 3and 6months＇ follow-up visit were analyzed.Results Of the 45 and 47eyes in the treatment and control groups,22 and 15 were basically cured,12 and 5had marked improvement,9and 20 were improved,2and 7failed in the treatment,with the effective rates being 75.56% and42.55%,respectively.In comparison with pre-treatment,the visual acuity in both control group and treatment group were improved（P〈0.05）.The numbers of children who had improvement of visual acuity after 2weeks,one month in the control group and treatment group were 26 and 31eyes,10 and 11eyes,respectively.The recurrence rate 6months after the treatment was50.00%in the control group and 16.28%in the treatment group.The effective rate of the treatment group was significantly superior to that of the control group（P〈0.05）.Conclusion Auricular pressure combined with Chinese medical herb treatment is effective in improving visual acuity,and had a higher efficacy,faster action,and lower recurrence rate in amblyopia children in comparison with simple herbal medicine treatment.