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多巴胺在近视形成中作用的研究进展 被引量:16

Advances in research on the role of dopamine in myopia
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摘要 多巴胺(DA)作为视网膜上一种重要的神经递质在近视的发生发展过程中起着重要作用.现主要针对实验近视过程中视网膜DA含量的变化,多巴胺能系统,多巴胺D1、D2受体在近视形成中的作用以及DA和其他近视相关信号分子之间的交互作用等进行探讨.为进一步探索近视形成机制,寻找治疗近视的药物提供思路和方法. Dopamine (DA) plays an important role in the onset and development of myopia as an important neurotransmitter in the retina.This article reviews recent research on the role of DA in myopia,including the change in retinal DA content during myopia progression,the role of the dopaminergic system,the functions of DA receptors D1 and D2 in myopia progression and the interaction of dopamine signaling with other transmitters related to myopia.This review may provide some clues for further insights into the mechanisms of myopia as well as a search for the treatment of myopia.
出处 《中华眼视光学与视觉科学杂志》 CAS CSCD 2015年第6期377-380,共4页 Chinese Journal Of Optometry Ophthalmology And Visual Science
基金 国家973计划项目(2011CB504604)
关键词 近视 多巴胺 形觉剥夺性近视 镜片诱导性近视 Myopia Dopamine Form-deprivation myopia Lens-induced myopia
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参考文献33

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