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Hepatotoxicity Associated with a Short Course of Rosuvastatin 被引量:3

Hepatotoxicity Associated with a Short Course of Rosuvastatin
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摘要 Statins reduce cardiovascular morbidity and mortality with dyslipidemia.Although generally well-tolerated,dose-dependent adverse events develop in 10%-15% patients.In addition,up to 3% patients have mildly elevated serum aminotransferase levels within the 1st year of therapy that are rarely associated with symptoms. Statins reduce cardiovascular morbidity and mortality with dyslipidemia.Although generally well-tolerated,dose-dependent adverse events develop in 10%-15% patients.In addition,up to 3% patients have mildly elevated serum aminotransferase levels within the 1st year of therapy that are rarely associated with symptoms.
机构地区 Division of Cardiology
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第12期1693-1694,共2页 中华医学杂志(英文版)
关键词 DRUG HEPATOTOXICITY ROSUVASTATIN Drug Hepatotoxicity Rosuvastatin
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参考文献5

  • 1Russo MW, Scobey M, Bonkovsky HL. Drug-induced liver injury associated with statins. Semin Liver Dis 2009;29:412-22.
  • 2Chalasani N. Statins and hepatotoxicity: Focus on patients with fatty liver. Hepatology 2005;41 :690-5.
  • 3Robert LT, Pharm D. Safety issues with statin therapy. J Am Pharm Assoc 2006;46:479-490.
  • 4Seaman WE, Ishak KG, Plotz PH. Aspirin-induced hepatotoxicity in patients with systemic lupus erythematosus. Ann Intern Med 1974;80: 1-8.
  • 5Bhardwaj SS, Chalasani N. Lipid-lowering agents that cause drug-induced hepatotoxicity. Clin Liver Dis 2007; II :597-613, vii.

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