消化系肿瘤患者口服化疗药物的依从性及相关影响因素

Adherence to oral chemotherapy and related factors in patients with gastrointestinal cancer

目的:了解消化系肿瘤患者口服化疗药物的依从性及影响因素,为制定有针对性的护理策略,提高患者服药依从性提供依据.方法:应用药片计数和问卷调查2种方法评价207例患有消化系肿瘤且口服化疗药物的患者的用药依从性并分析相关因素.结果:(1)消化系肿瘤患者口服化疗药依从性为:68.6%.依从性不佳的表现是:忘记、因不良反应大自停药物、因症状改善自行停药、外出未带药;(2)依从性受性别、年龄、文化程度、有无提醒方式影响(P<0.05),而与诊断、住院次数无关(P>0.05).结论:消化系肿瘤患者口服化疗药物依从性有待提高,尤其是男性,高龄,文化程度低及没有任何提醒方式的患者,提示护理工作应加强用药指导及随访,以期提高患者服药依从性,保证治疗顺利进行.

AIM： To assess the adherence to oral chemotherapy and explore related factors in patients with gastrointestinal cancer, in order to provide a basis for nursing intervention and improve patient adherence.METHODS： This study investigated 207 patients with gastrointestinal cancer who received oral chemotherapy by pill counting and questionnaire survey.RESULTS： The rate of adherence to oral chemotherapy in patients with gastrointestinal cancer was 6 8. 6 %. Thereas on sforlow adherence included forgetting to take, adjusting the dose for side effects, not taking drugs when out, and stopping medication as symptoms relieved. Factors related to adherence included gender, age, education level and whether there was a remainder（P 〈 0.05）, however, diagnosis and hospitalized frequency had no significant impact on adherence（P 〉 0.05）. CONCLUSION： The adherence of gastrointestinal cancer patients to chemotherapy should be strengthened, especially in high-risk patients, like elderly patients, male patients, those with a low education level and those with no remainder.