女性迟发性痤疮中医体质类型与中医证候分布的关系

Relation between Chinese Medical Constitutions of Female Patients with Late-onset Acne:an Epidemiological Investigation

目的探讨女性迟发性痤疮及其证候与中医体质的关系。方法采用王琦教授中医体质九分法及其《中医体质分类标准》量表制定的体质调查问卷,对365例女性迟发性痤疮患者与135名正常受试者（对照组）进行中医体质调查。结果患者组中医体质类型依次为湿热质、阴虚质、平和质、阳虚质、血瘀质、气郁质、气虚质、痰湿质、特禀质,与对照组比较,差异有统计学意义（χ~2=85.206,P〈0.01）。365例患者中,冲任失调证、血瘀或痰凝证、湿热证和风热证分别为1 14例（31.23%）,108例（29.59%）,83例（22.74%）,60例（16.44%）。不同中医证型的中医体质类型分布比较,差异亦有统计学意义（χ~2=105.671,P〈0.01）。患者组和对照组体质分布不同,患者组多见偏颇体质,对照组多见平和体质。二分类Logistic回归分析示甜食、喜清淡、喜炙烤、好咖啡、紧张情绪、工作压力、家庭压力为女性迟发性痤疮发病的影响因素,其中喜清淡为保护因素,余均为不利因素。结论女性迟发性痤疮患者发病及其发病后的证候类型与体质相关。

Objective To explore the correlation between syndrome types of late-onset acne female patients and constitutions of Chinese medicine（CM）.Methods A questionnaire was performed in365 late-onset acne female patients and 135 healthy subjects（as the control） using Professor WANG Qi’s methods and Standards for Chinese Medical Constitutions Classification.Results Their CM constitutions were sequenced as damp-heat constitution,yin-deficiency constitution,balanced constitution,yang-deficiency constitution,blood-stasis constitution,qi-stagnation constitution,qi-deficiency constitution,phlegm-damp constitution,inherited special constitution,with statistical difference when compared with those of the control group（χ~2=85.206,P 〈0.01）.In the 365 female late-onset acne patients,114（31.23%） were with Chongren imbalance syndrome,108（29.59%） were with blood stasis or coagulated phlegm syndrome,83（22.74%） were with dampness heat syndrome,and 60（16.44%） were with wind heat syndrome.There was statistical difference in CM constitution distributions among different CM syndrome types（χ~2=105.671,P〈0.01）.The distribution of CM medical constitutions was different between the two groups.Biased constitutions were often seen in the patient group,while balanced constitution was often seen in the control group.Binary Logistic regression analysis indicated that influencing factors covered sweet food,light diet,roasted food,coffee,stress,work pressure,and family pressure.Of them light diet was one protective factor,while the rest were adverse factors.Conclusion The etiology and syndrome types of female late-onset acne female patients were associated with CM constitution.