乳腺癌浸润淋巴细胞对新辅助化学疗法反应的预测及与预后的关系
被引量:1
摘要
近年来大量研究认为肿瘤浸润淋巴细胞是宿主免疫系统对肿瘤抗原存在免疫反应的标志,并且可以作为预测乳腺癌患者对蒽环/紫杉类新辅助化学疗法反应的有效指标。在三阴乳腺癌患者中,乳腺癌浸润淋巴细胞可作为一项判断预后的可靠指标。
出处
《华西医学》
CAS
2015年第6期1179-1182,共4页
West China Medical Journal
参考文献54
-
1Desantis C, Ma JM, Bryan L, et al. Breast cancer statistics, 2013[J]. CA Cancer J Clin, 2014, 64(1): 52-62.
-
2Pernas Simon S. Neoadjuvant therapy of early stage human epidermal growth factor receptor 2 positive breast cancer: latest evidence and clinical implications[J]. Ther Adv Med Oncol, 2014, 6(5): 210-221.
-
3Rampurwala MM, Rocque GB, Burkard ME. Update on adjuvant chemotherapy for early breast cancer[J]. Breast Cancer (Auckl), 2014, 8: 125-133.
-
4Bhattacharyya T, Sharma SC, Yadav BS, et al. Outcome of neoadjuvant chemotherapy in locally advanced breast cancer: atertiary care centre experience[J]. Indian J Med Paediatr Oncol, 2014, 35(3): 215-220.
-
5Li Q, Liu M, Ma F, et al. Circulating miR-19a and miR-205 in serum May predict the sensitivity of luminal A subtype of breast cancer patients to neoadjuvant chemotherapy with epirubicin plus paclitaxel[J]. PLoS One, 2014, 9(8): e104870.
-
6Wang K, Deng QT, Liao N, et al. Tau expression correlated with breast cancer sensitivity to taxanes-based neoadjuvant chemotherapy[J]. Tumour Biol, 2013, 34(1): 33-38.
-
7Yu KD, Liu GY, Zhou XY, et al. Association of HER-2 copy number and HER-2/CEP-17 ratio with neoadjuvant taxane-containing chemotherapy sensitivity in locally advanced breast cancer[J]. Oncologist, 2012, 17(6): 792-800.
-
8Tokuda E, Seino Y, Arakawa A, et al. Estrogen receptor-α directly regulates sensitivity to paclitaxel in neoadjuvant chemotherapy for breast cancer[J]. Breast Cancer Res Treat, 2012, 133(2): 427-436.
-
9Kaufmann M, Hortobagyi GN, Goldhirsch A, et al. Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: an update[J]. J Clin Oncol, 2006, 24(12): 1940-1949.
-
10Jones RL, Smith IE. Neoadjuvant treatment for early-stage breast cancer: opportunities to assess tumour response[J]. Lancet Oncol, 2006, 7(10): 869-874.
二级参考文献52
-
1徐林,蒋正刚,李宝华,熊思东.小鼠乳腺癌实验动物模型中CD4^+ CD25^+调节性T细胞的变化及意义[J].复旦学报(医学版),2006,33(6):736-740. 被引量:13
-
2Sakaguchi S,Sakaguchi N,Asano M,et al.Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25).Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.J Immunol,1995;155(3):1151-1164.
-
3Bach JF.Regulatory T cells under scrutiny.Nat Rev Immunol,2003;3(3):189-198.
-
4Von Boehmer H.Mechanisms of suppression by suppressor T cells.Nat Immunol,2005;6(4):338-344.
-
5Joncker NT,Marloie MA,Chernysheva A,et al.Antigen-independent accumulation of activated effector/memory T lymphocytes into human and murine tumors.Int J Cancer,2006;118(5):1205-1214.
-
6Pagès F,Berger A,Camus M,et al.Effector memory T cells,early metastasis,and survival in colorectal cancer.N Engl J Med,2005;353(25):2654-2666.
-
7Kawaida H,Kono K,Takahashi A.Distribution of CD4^+CD25^high regulatory T-cells in tumor-draining lymph nodes in patients with gastric cancer.J Surg Res,2005;124(1):151-157.
-
8Lécureuil C,Combadière B,Mazoyer E,et al.Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients.Blood,2007;109(9):3649-3657.
-
9Kleinewietfeld M,Puentes F,Borsellino G,et al.CCR6 expression defines regulatory effector/memory-like cells within the CD25^+CD4^+ T-cell subset.Blood,2005;105(7):2877-2886.
-
10Powell DJ,Rosenberg SA.Phenotypic and functional maturation of tumor antigen-reactive CD8^+ T lymphocytes in patients undergoing multiple course peptide vaccination.J Immunother,2004;27(1):36-47.
共引文献3
-
1任宇,姚新生,杨伟明.调节性T细胞和乳腺癌治疗研究近展[J].中国普通外科杂志,2014,23(11):1567-1571. 被引量:1
-
2蒋正华,韩旭.肿瘤浸润T淋巴细胞在乳腺癌原发灶中的表达与预后的关系[J].中国现代医生,2015,53(6):13-16. 被引量:8
-
3周涯,李永菊,周洪练,任社华.局部湿热联合微波消融对乳腺癌荷瘤小鼠CD4^+ CD25^+调节性T淋巴细胞比例和功能的影响[J].基础医学与临床,2015,35(9):1188-1193. 被引量:2
同被引文献5
-
1杨瑞,王淑君,张颖.亚甲蓝作为淋巴示踪剂的研究与展望[J].中国药剂学杂志(网络版),2009(2):65-71. 被引量:16
-
2马宏岩.乳腺癌微创治疗的研究进展[J].中国普外基础与临床杂志,2010,17(3):214-218. 被引量:25
-
3吴硕东,范莹,希渥,彭观景,殷振华.单切口乳腺癌保留乳房手术并腔镜下腋窝淋巴结切除术二例[J].中华乳腺病杂志(电子版),2010,4(5):62-63. 被引量:6
-
4陈翔,王水.乳腺癌前哨淋巴结活检研究现状及进展[J].中国普外基础与临床杂志,2011,18(1):98-102. 被引量:12
-
5王水,范萍,武正炎.乳腺癌前哨淋巴结淋巴细胞亚群的初步研究[J].中华肿瘤杂志,2004,26(4):220-222. 被引量:11
二级引证文献12
-
1符岸秋,郭泽霞,卓恩挺,张秀燕,罗香香.微创置管接负压吸引器引流联合抗菌药物治疗乳腺癌术后皮瓣下积液伴感染的临床疗效及对TNF-α与IL-8和PCT的影响[J].中华医院感染学杂志,2018,28(23):3635-3639. 被引量:12
-
2王丽君.前哨淋巴结活检替代治疗对早期乳腺癌患者肩关节功能及预后的影响[J].河南医学研究,2017,26(13):2433-2434.
-
3喻满成,王伟,范威,许娟,吴新红,冯尧军.皮瓣点式缝合联合万特普安防治乳腺癌术后皮下积液疗效观察[J].肿瘤防治研究,2018,45(3):163-166. 被引量:10
-
4韦钰蘅,秦宏兴,周宾经.Halsted-Meyer纵切口与Stewart横切口在乳腺癌根治术中的应用价值对比[J].临床医学工程,2018,25(8):1045-1046. 被引量:2
-
5李蒙玲,涂兴峰.手术切口选择对乳腺癌前哨淋巴结活检的影响研究[J].吉林医学,2018,39(4):726-728. 被引量:2
-
6乔恩奇,杨红健,金菊.前哨淋巴结活检术用于早期三阴性乳腺癌患者的疗效研究[J].中国现代医生,2019,57(10):95-97. 被引量:3
-
7许伟伟,孙新儒.43例乳腺癌改良根治术后皮下积液的危险因素分析[J].实用癌症杂志,2019,34(9):1482-1484. 被引量:13
-
8刘学仁.引流管连接负压瓶引流法辅助治疗对乳腺癌术后皮瓣下积液伴感染患者的影响[J].中国民间疗法,2019,27(20):66-69. 被引量:1
-
9朱祝.不同切口处理方式对中老年乳腺癌患者术后皮下积液发生情况的影响[J].健康女性,2020,12(5):18-18.
-
10李晓梅,龚君,胡艺.乳腺癌患者术后皮下积液发生现状及影响因素分析[J].当代医学,2021,27(17):145-146. 被引量:2
-
1杨红文,陈忠东,周波,秦永喜,赵强.S期细胞比率对局部晚期宫颈癌新辅助化疗敏感性的预测价值[J].现代妇产科进展,2011,20(2):137-138. 被引量:2
-
2乔杰奇,李峰,邱劲松,周总光.直肠癌术后应用康艾注射液辅助化学疗法的评价[J].华西医学,2013,28(9):1420-1422. 被引量:6
-
3李力军,刘春燕,杜伟生,王玲娟,连正杰,张文莉,范洁,崔永旺,郭怡辉,汪金钟.Ⅲ期乳腺癌的新辅助化疗[J].中国肿瘤临床,1995,22(4):248-251. 被引量:11
-
4食管肿瘤[J].国外科技资料目录(医药卫生),1998(8):132-134.
-
5卵巢肿瘤[J].国外科技资料目录(医药卫生),1998(10):151-152.
-
6胃肿瘤[J].国外科技资料目录(医药卫生),1998(12):118-128.
-
7王娟,陈峻青,王舒宝,王梅先,吴烨秋.不能切除进展期胃癌新辅助化疗的评价——临床、组织学效果[J].中华肿瘤杂志,1997,19(1):65-68. 被引量:16
-
8胃肿瘤[J].国外科技资料目录(医药卫生),1998(10):135-139.
-
9胃肿瘤[J].国外科技资料目录(医药卫生),1997(8):143-146.
-
10刘晓平.乳癌化学疗法的现状和展望 专辑──乳癌的新辅助化学疗法[J].日本医学介绍,1994,15(4):155-157.