格栅光凝治疗缺血型视网膜分支静脉阻塞黄斑水肿疗效观察

Observation of curative effect on laser in the treatment of macular edema with ischemic branch retinal vein occlusion

目的观察532mm激光治疗缺血型视网膜分支静脉阻塞黄斑水肿治疗效果，对比行黄斑区格栅光凝与未行黄斑区格栅光凝临床疗效是否有差异。方法对2014年1～7月在抚顺市眼病医院经回顾性分析视网膜分支静脉阻塞（BRVO）继发黄斑水肿患者30例30只眼，A组15例行无灌注区视网膜激光光凝联合黄斑区格栅光凝治疗；B组15例单纯行无灌注区视网膜激光光凝，观察治疗后1、3、6个月的黄斑水肿消退情况。结果A组治疗前黄斑区中心凹厚度（573．20±155．34）μm，治疗后1、3、6个月黄斑区中心凹厚度分别为（534．40±151．94）Ixm、（415．26±120．19）μm、（286．13±81．38）μm，治疗后较治疗前黄斑水肿均减轻，差异有统计学意义（P〈0．05）。B组治疗前黄斑区中心凹厚度（585．86±160．19）μm，治疗后1、3、6个月黄斑区中心凹厚度分别为（568．80±159．04）μm、（525．20±143．49）μm、（426．20±116．46）μm，治疗后较治疗前黄斑水肿均减轻，差异有统计学意义（P〈0．05）。治疗后1、3、6个月两组问比较，1个月时黄斑区中心凹厚度无差异，3、6个月时差异有统计学意义（P〈O．05）。治疗后6个月内两组均无视网膜新生血管形成。结论黄斑区格栅光凝能有效地减轻视网膜分支静脉阻塞黄斑水肿，行无灌注区视网膜激光光凝能有效预防新生血管形成。

Objective To observe the curative effect on 532nm laser in the treatment of macular edema with ischemie branch retinal vein occlusion, contrast for macular grid photocoagulation with no clinical efficacy of macular grid photocoagulation. Methods A retrospective analysis of branch retina/ vein occlusion （BRVO） in patients with macular edema who was in Fushun Ophthalmology hospital during January-July 2014 in 30 eyes of 30 cases, 15 cases in group A with non perfusion area retinal laser photocoagulation combined with macular grid photocoagulation treatment; 15 cases in group B with non-perfusion area laser photocoagulation, Observed treatment after 1 month, 3 months, 6 months of macular edema subsided. Results The group prior A treatment macular foveal thickness was （573.20±155.34）μm, after 1 month, 3 months and 6 months of treatment of macular fo- veal thickness was （534.40±151.94）μm, （415.26±120.19）μm, （286.13±81.38）μm, after treatment than be- fore treatment, macular edema was relieved in all patients, the difference had statistical significance （P〈0.05）. The group B prior treatment macular foveal thickness was （585.86±160.19）μm, after 1 month, 3 months and 6 months of treatment of macular foveal thickness was （568.80±159.04）μm, （525.20±143.49）μm, （426.20±116.46）μm, after treatment than before treatment, rnacular edema was re- lieved in all patients, the difference had statistical significance （P 〈0.05）. Effect of different periods respectively in the two groups after treatment were compared, the difference was not statistically sig- nificant after 1 month of treatment （P 〉0.05）; 3 months and 6 months after treatment, the differenc- es were statistically significant （P 〈0.05）; 6 months after treatment in two groups had no retinal neo- vascularization. Conclusions Macular grid photocoagulation can effectively reduce the macular ede- ma with branch retinal vein occlusion, for non-perfusion area laser photocoagulation is effective in preventing the retinal neovascularization.