广西专项示范区≥15岁HIV阳性病例特征及筛查检出风险

Characteristics and screening risk factors screening of HIV-positive patients aged over 15 years in Guangxi HIV/AIDS special demonstration areas

目的了解筛查报告与常规报告≥15岁HIV阳性病例特征的差异,分析影响艾滋病筛查发现HIV阳性病例的因素。方法通过对广西艾滋病专项示范区常住居民进行HIV抗体检测,收集筛查报告和常规报告HIV阳性病例的基本信息,用PASW Statistics18分析两者之间的差异。结果共检测了1 057 742名常住人口,发现1 218例HIV阳性病例,HIV阳性检出率为1.15‰。年龄30~44岁（OR=4.45,95%CI：2.51~7.92）、45~59岁（OR=5.40,95%CI：2.97~9.82）、≥60岁（OR=7.76,95%CI：4.06~14.83）、小学文化（OR=2.49,95%CI：1.36~4.59）、初中文化（OR=3.34,95%CI：1.84~6.06）和首次CD4＋计数≥200个/μL（OR=1.52,95%CI：1.15~2.01）等特征的HIV阳性病例被筛查发现的风险较高;非农民（OR=0.59,95%CI：0.40~0.88）和其他传播（OR=0.17,95%CI：0.07~0.38）等特征的HIV阳性病例被筛查发现的风险较低。结论广西艾滋病专项示范区中可能存在较多既往感染的HIV阳性病例,应在继续加强常规检测的基础上,对疫情较严重的地区或重点人群开展HIV筛查工作。

Objective To understand the differences of characteristics between screening and routine reports of HIV- positive cases over age of 15 years and analyze the factors influencing AIDS screening. Methods Anti-HIV antibodies in permanent residents were detected and general information of screening report and routine report of HIV positive patients in Guangxi HIV/AIDS special demonstration project areas was gathered and PASW Statisticsl8 was used to analyze the differences between screening report and routine reports of HIV positive cases. Results A total of 1 057 742 permanent residents were screened and 1 218 HIV positive cases were detected with a HIV-positive rate of 1.15%o. The relatively high risk factors associated with HIV infection were population aged 30~44 years （OR=4.45,95% CI：2.51 ~ 7.92）, 45~59 years （OR= 5.40, 95% CI： 2.97 ~ 9.82）,≥60 years （OR=7.76, 95% CI： 4.06 ~ 14.83）, primary school education （0R=2.49, 95% CI.＇1.36 ~ 4.59）,junior middle school education （OR=3.34,95% CI： 1.84 ~ 6.06） and the first test CD4＋count~〉200cell/IxL （0R=1.52,95% CI.＇1.15~2.01）. While the relatively low risk factors related with HIV infection were farmers （0R=0.59,95% CI： 0.40 ~ 0.88） and other transmission routes （OR=0.17, 95% CI：0.07 ~ 0.38）. Conclusion There might be many previous infection HIV positive cases hiding in Guangxi HIV/AIDS special demonstration areas. On the basis of strengthening routine detection of HIV. positives , HIV screening in HIV epidemic areas or focus groups be carried out.