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脊髓电刺激治疗心血管疾病的应用进展 被引量：2

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摘要 脊髓电刺激（spinal cord stimulation,SCS）是指将SCS器的电极安放于椎管的硬膜外间隙,通过电流刺激脊髓后柱的传导束和后角感觉神经元,从而达到治疗疼痛或其它疾病目的的一种方法[1-2].SCS装置包括一个电极、一个脉冲发生器和延长导线,目前已被国外疼痛康复科广泛应用于治疗各种类型的疼痛（心绞痛、复杂区域疼痛综合征、缺血性肢体疼痛、腹痛、宫颈癌痛等）[1-10].近期研究表明,SCS可增加缺血区域血流灌注,降低心肌耗氧量,减少心绞痛发作次数和程度[1-14];改善心脏收缩功能和同步性运动功能[15-20];调节心脏自主神经再平衡,抑制心脏内在自主神经活性[21-30]等.在此,本文就SCS在缓解心绞痛症状、改善心功能、抑制心律失常等方面的应用进展做一综述.
作者 赵圣刚 江力勤
机构地区 浙江省嘉兴市第二医院心内科
出处 《中华物理医学与康复杂志》 CAS CSCD 北大核心 2015年第6期470-472,共3页 Chinese Journal of Physical Medicine and Rehabilitation
基金 浙江省自然科学基金资助项目（Y2110934）
关键词 脊髓电刺激 心血管疾病 临床治疗 患者
分类号 R54 [医药卫生—心血管疾病]
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参考文献30

  • 1B(o)rjesson M,André11 P,Mannheimer C,et al.Spinal cord stimulation for long-term treatment of severe angina pectoris:what does the evidence say[J].Future Cardiol,2011,7(6):825-833.
  • 2McGillion M,L'Allier PL,Arthur H,et al.Recommendations for advancing the care of Canadians living with refractory angina pectoris:a Canadian Cardiovascular Society position statement[J].Can J Cardio1,2009,25 (7):399-401.
  • 3Zipes DP,Svorkdal N,Berman D,et al.Spinal cord stimulation therapy for patients with refractory angina who are not candidates for revascularization[J].Neuromodulation,2012,15 (6):550-558.
  • 4Lanza GA,Barone L,Di Monaco A.Effect of spinal cord stimulation in patients with refractory angina:evidence from observational studies[J].Neuromodulation,2012,15 (6):542-549.
  • 5Falowski S,Celii A,Sharan A.Spinal cord stimulation:an update[J].Neurotherapeutics,2008,5 (1):86-99.
  • 6Bondesson SM,Jakobsson U,Edvinsson L,et al.Hospital utilization and costs for spinal cord stimulation compared with enhanced external counterpulsation for refractory angina pectoris[J].J Eval Clin Pract,2013,19(1):139-147.
  • 7Andréll P,Ekre O,Eliasson T,et al.Cost-effectiveness of spinal cord stimulation versus coronary artery bypass grafting in patients with severe anginapectoris-long-term results from the ESBY study[J].Cardiology,2003,99 (1):20-24.
  • 8Deer TR.Spinal cord stimulation for the treatment of angina and peripheral vascular disease[J].Curr Pain Headache Rep,2009,13 (1):18-23.
  • 9Eckert S,Horstkotte D.Management of angina pectoris:the role of spinal cord stimulation[J].Am J Cardiovasc Drugs,2009,9 (1):17-28.
  • 10Foreman RD,Linderoth B.Neural mechanisms of spinal cord stimulation[J].Int Rev Neurobio1,2012,107 (1):87-119.

二级参考文献53

  • 1Patlak JB, Ortiz M. Two models of gating during late Na channel currents in frog Sartorius musics. J Gen Physiol, 1986,87 : 305- 326.
  • 2Maltsev VA, Sabbah HN, Higgins RS, et al. Uhraslow inactivating sodium current in human ventricular cardiomyocytes. Circulation, 1998,98:2545-2552.
  • 3Vassalle M, Bocchi L, Du F. A slowly inactivating sodium current (INa2) in the plateau range in canine cardiac Purkinje single cells. Exp Physiol,2007 ,92 :161-173.
  • 4Zygmunt AC, Eddlestone GT,Thomas GP, et al. Larger late sodium conductance in M cells contributes to electr ICaL heterogeneity in canine ventricle. Am J Physiol Heart Circ Physiol, 2001,281 : H689 -H697.
  • 5Sakmann BF, Spindler A J, Bryant SM, et al. Distribution of a per- sistent sodium current across the ventrieular wall guinea pigs. Cire Res,2000,87:910-914.
  • 6Zaza A, Belardinelli L, Shryock JC, et al. Pathophysiology and pharmacology of the cardiac late sodium current. Pharmacology Therapeutics,2008,119:326-339.
  • 7Makielski JC, Farley AL. Na^+ current in human ventricle :implica- tion for sodium loading and homeostasis. J Cardiovasc Electrophysi- ol,2006,17 ( suppl 1 ) : s15-20.
  • 8Giansanti V, Santamafia G, Torriglia A. Fluorescence properties of the Na^+/H^+ exchanger inhibitor HMA ( 5-( N, N-hexamethylene ) amiloride) are modulated by intracellular pH. Eur J Histochem, 2012,56 : 16-19.
  • 9Gyorke S, Gyorke I, Lukyanenko V, et al. Regulation of sarcoplas- mic recticulum calcium release by lum INaL calcium in cardiac muscle. Front Biosci ,2002,1 : 1454-1463.
  • 10Maier LS, Zhang T, Chen L, et al. Transgenic CaMMKII detaC overexpression uniquely alter cardiac myocyte Ca^2+ handing : re- duced SR Ca^2+ load and activated SR Ca^2+ release. Circ Res, 2003,92:904-911.

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中华物理医学与康复杂志
2015年 第6期

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