摘要
埃博拉病毒(Ebola virus,EBOV)引起的埃博拉病毒病(Ebola virus disease,EVD)是迄今发现的最凶猛的烈性传染病之一。EVD传染性强、死亡率高,目前尚无特效治疗方法。EBOV感染后能够引起机体出现一系列免疫反应,宿主出现特异性及非特异性抗病毒免疫缺陷是EVD致死的重要原因。本文就EBOV对人体天然免疫功能的影响及其相应对策的研究进展作一综述。
Ebola virus disease(EVD)caused by Ebora virus(EBOV)is one of the most violent infectious disease so far.It is so highly infective and fatal that there has been no effective treatment until now.Ebola viral infection can cause a series of immune responses.Specific and nonspecific antiviral innate immune deficiency in the hosts is a recognized important reason for EVD associated death.This paper reviews the influence of EBOV on innate immune reaction of humans and the corresponding countermeasures.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2015年第6期607-611,共5页
Academic Journal of Second Military Medical University