比阿培南临床使用药物利用评价分析

Evaluation and analysis of clinical use of biapenem

目的:通过药物利用评价(drug utilization evaluation,DUE)方法,评价比阿培南临床使用的合理性与规范性,为促进临床合理用药提供参考。方法:依据"比阿培南DUE标准"对某医院2014年住院患者使用比阿培南332例病历进行回顾性分析。结果:(1)抗菌药物管理:微生物送检率82.2%(80%),会诊流程符合率51.3%(100%),病程记录符合率83.4%(100%),处方权限符合率97.3%(100%);(2)用药指征:适应症98.2%(90%);(3)用药过程:给药途径、溶媒选择、配伍禁忌正确率100%(100%);疗效监测项符合率80.4%(85%);(4)用药结果有效率78.6%(80%)。结论:医院比阿培南临床使用整体情况较好,但仍存在一些不足,医院应针对存在问题进行干预和整改,确保抗菌药物的规范合理使用。"比阿培南DUE标准"对促进临床规范、合理使用比阿培南有一定作用。

Objective：To evaluate the clinical use of biapenem standardability and rationality with DUE mode and apply guide-lines for its rational clinical use. Methods：According to biapenem DUE standard,332 patients who received biapenem in one hospital were analyzed. Results：（1）Antibacterials management：Microbial inspection rate was 82. 2% （80%）;the coincidence rate of consul-tation process 51. 3% （100%）;the coincidence rate of course record 83. 4% （100%）;the coincidence rate of prescription privileges was 97. 3% （100%）;（2）The indications of drug use：suitable rate was 98. 2%（90%）;（3）Medication process：the correct rate of the administration route,solvent selection and incompatibility were 100% （100%）;and effect of monitoring compliance rate was 80. 4%（85%）;（4）Medication effective rate was 78. 6% （80%）. Conclusion：The clinical use of biapenem was quite well in one hospital, but there are some shortcomings. Hospital should do some intervention and rectification for existing problems to ensure the rational use of antimicrobial drugs. Biapenem DUE standard had certain effect on promoting the rational use of biapenem in clinical.