磷酸二酯酶5抑制剂在心血管疾病治疗中的应用

Uses of phosphodiesterase 5 inhibitors in treatment of cardiac disease

磷酸二酯酶5抑制剂通过抑制磷酸二酯酶,延迟环磷酸鸟苷的分解,从而发挥血管平滑肌扩张作用。磷酸二酯酶5抑制剂在心力衰竭、肺动脉高压、高原肺水肿、高原肺动脉高压、高血压、雷诺综合征等的治疗中发挥重要作用。

Phosphodiesterase 5 inhibitors exert dilation of vascular smooth muscle by inhibiting phosphodiesterase and delaying break of cyclic guanosine 3＇, 5＇-monophosphate. Phosphodiesterase 5 inhibitors exert important effects in the treatment of heart failure, pulmonary hypertension, high- altitude pulmonary edema, high-altitude pulmonary hypertension, hypertension, Raynaud＇ s phenomenon.