炎性反应与主动脉夹层诊断及预后关系的研究进展

Relations of inflammatory reactions with diagnosis and prognosis of aortic dissection: recent progress

主动脉夹层(AD)是严重危及患者生命的心血管系统疾病之一,其病情凶险,发病机制复杂。近年来炎性反应在AD发生发展中的作用逐渐受到重视,并发现炎性反应与AD的发病及预后关系密切,笔者就炎性反应参与AD发生发展的可能机制,炎性标记物与AD诊断的关系,炎性反应对不同分型AD预后的影响作一综述,并对面临的问题及未来的展望加以阐述。

As one of the life-threatening diseases in cardiovascular system, aortic dissection（AD） is an extremely dangerous condition with a complex pathogenesis. In recent years, the role of inflammatory reactions in the development of aortic dissection has increasingly attracted great attention, and many findings have shown that inflammatory reactions contribute greatly to the pathophysiology and outcomes of AD. In this article, the authors address the possible mechanisms for inflammatory reactions participating in the occurrence and development of AD, the relationship between markers of inflammation and diagnosis of AD, and the influence of inflammatory reactions on prognosis of dif erent types of AD, as well as the current problems and future prospects.