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219例抗核抗体阳性红斑狼疮患者TRUST试验结果分析

Analysis of TRUST Results of 219 Lupus Erythematosus Patients with Positive Antinuclear Antibody
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摘要 目的:探讨红斑狼疮患者TRUST试验阳性与抗核抗体ANA阳性的相关性。方法:选取219例ANA阳性的红斑狼疮患者,采用TRUST试验对患者血清进行检测,分析TRUST阳性患者中ANA滴度与型别分布状况。结果:红斑狼疮患者中TRUST阳性8例,阳性率为3.7%,其中ANA为均质型的患者阳性率显著多于其他类型(P<0.05),不同ANA滴度患者TRUST阳性率无明显差异(P值均>0.05)。结论:红斑狼疮患者TRUST检测阳性可能与ANA密切相关。 Objective:To investigate the correlation between TRUST test positive and antinu-clear antibody ( ANA) test positive in lupus erythematosus ( LE) patients.Methods:219 LE pa-tients with positive ANA were tested by TRUST assay,and the distribution of ANA titer and type in positive TRUST patients were analyzed.Results:In 219 LE patients, 8 cases were TRUST posi-tive, the positive rate was 3.7%.The positive rate of ANA homogeneous type was significantly higher than that of granules, nucleolus or centromere type ( P 〈0.05 ) .Conclusion:Positive TRUST result in LE patients may be associated with ANA.
出处 《皮肤性病诊疗学杂志》 2015年第3期167-169,共3页 Journal of Diagnosis and Therapy on Dermato-venereology
基金 广东省科技计划项目(编号:2011B031800225 2012B031800175) 广东省医学科学技术研究基金(编号:C2012032)
关键词 红斑狼疮 抗核抗体 TRUST Lupus erythematosus Antinuclear antibody TRUST
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