广东省珠海市女性性工作者梅毒感染相关因素研究

Study on Associated Factors of Syphilis Infection among Female Sex Workers in Zhuhai City of Guangdong Province

目的：探讨影响珠海市女性性工作者（FSW）梅毒感染的相关因素。方法：采用病例对照研究方法，以珠海FSW人群中的梅毒病人为病例组，1∶4匹配选择梅毒初筛阴性者为对照组。通过广东省梅毒综合防治示范区FSW人群调查专用问卷获取一般情况、性行为特征、毒品接触史、梅毒知晓情况、精神障碍情况等信息，采用拟合条件Logistic回归模型对数据进行单因素与多因素分析。结果：调查发现27名梅毒阳性感染者，对照组匹配108名。单因素分析显示，周平均接客6～15人是感染梅毒的危险因素，OR值为2.87（95％CI：1.04～7.87）；而一个月内每次都使用安全套和知晓梅毒预防知识是感染梅毒的保护因素，OR值分别为0.14（95％CI：0.09～0.42）和0.29（95％CI：0.17～0.90）。多因素分析显示，一个月内每次都使用安全套和知晓梅毒预防知识是感染梅毒的保护因素，OR值分别为0.25（95％CI：0.11～0.90）和0.34（95％CI：0.21～1.25）。结论：坚持每次都使用安全套和知晓梅毒预防知识是感染梅毒的保护因素。

Objective：To explore related risk factors of Syphilis infection among female sex workers（ FSW） in Zhuhai.Methods：A case-control study was conducted.FSWs with syphilis in Zhuhai were indentified as case group, and each case matched by 4 syphilis-nega FSWs.FSWs survey questionnaire was designed by Guangdong Initiative for Comprehensive Control of Syphilis （ GICCS） and used in the study in order to collect messages including group behaviors, syphilis-related knowledge, drug abuse and mental health.Fitting conditional logistic regression model was applied for univariate and multivariate analysis.Results：In this study, 27 Syphilis positive FSWs were identified and 108 controls were matched.Data from univariate analysis showed that, 6-15 sexual customers per week were risk factors for syphilis infeetion, with OR values of 2.87 （ 95%CI：1.04 ~7.87 ） .Syphilis-related knowledge and consistent condom use in recent month were protective factors with OR values as 0.14（95%CI：0.09~0.42）and 0.29（95%CI：0.17~0.90） respectively.Multivariate analysis showed that, syphilis-related knowledge and consistent condom use in recent month were protective factors with OR values as 0.25 （ 95%CI：0.11 ~0.9 0 ） and 0.34 （ 9 5%CI：0.2 1 ~1.2 5 ） respectively .Conclusions：Syphilis-related knowl-edge and consistent condom use were protective factors related to syphilis transmission.