摘要
急性脑缺血是目前严重威胁人类健康的重大疾病,其病理生理机制复杂,临床治疗应用的药物非常有限,而且作用特点和效果仍不明确。该文总结了目前我国临床用于治疗急性脑缺血药物的作用和机制,比较了各种药物的特点,结合近年来国内外抗急性脑缺血药物研究的进展,探讨了治疗急性脑缺血药物的发展前景。
Acute cerebral ischemia is one of the most threating diseases to human health, with extremely complex pathophysiology. Considering the limited number of anti-cerebral ischemia drugs and their unclear mechanisms, there are almost no ideal therapeutic drugs in clinical. In this paper,we summarized the function characteristics of current clinical drugs, compared their efficacy, reviewed the related articles at home and abroad in recent years, and elaborated the research situation of various tvnes of anti-cerehral ischemia drugs.
出处
《神经药理学报》
2014年第4期50-58,共9页
Acta Neuropharmacologica
基金
国家"重大新药创制"科技重大专项项目(No.2012ZX09103-101-078)
国家"重大新药创制"科技重大专项项目(No.2013ZX09102106)
关键词
脑缺血
神经保护
溶栓
cerebral ischemia
neuroprotection
thrombolysis.
