脑卒中后痫性发作早期预测因素

Early predictive factor for epileptic seizure after stroke

目的探讨脑卒中后痫性发作的早期预测因素。方法对脑卒中后痫性发作的脑卒中病例的临床资料进行回顾性分析。结果研究期间1031例连续脑卒中病例中79例出现脑卒中后痫性发作,占7.7%。724例缺血性脑卒中、291例颅内出血及16例蛛网膜下腔出血患者中,分别出现脑卒中后痫性发作44例、30例和5例,各占6.1%、10.3%和31.3%。出现脑卒中后痫性发作的患者入院时美国国立卫生研究院脑卒中量表(NIHSS)评分显著高于无痫性发作的患者[(21.8±8.3)分VS(13.9±7.6)分,P<0.01]。多元回归分析提示入院时NIHSS评分是发生脑卒中后痫性发作的独立预测因素(P<0.05)。结论脑卒中后痫性发作常见于脑卒中患者,脑卒中严重程度是脑卒中后痫性发作的预测因素。

Objective To investigate early predictive factor for epileptic seizure after stroke. Methods A retrospective analysis was made on clinical data of patients with epileptic seizure after stroke. Results Among 1031 consecutive stroke patients, there were 79 cases of them had epileptic seizure after stroke, accounting for 7.7%. In 724 cases of ischemic stroke, 291 cases of intracranial hemorrhage, and 16 cases of subarachnoid hemorrhage, there were respectively 44 cases, 30 cases, and 5 cases with epileptic seizure after stroke, accounting for 6.1%, 10.3% and 31.3%. Patients with epileptic seizure after stroke had much higher admission national institutes of health stroke scale（NIHSS） score than those without epileptic seizure [（21.8±8.3） points VS（13.9±7.6） points, P〈0.01]. Multivariate regression analysis showed that admission NIHSS score was the independent predictive factor for epileptic seizure after stroke（P〈0.05）. Conclusion Epileptic seizure after stroke mainly occurs stroke patients, and stroke severity is the predictive factor for epileptic seizure after stroke.