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急性冠状动脉综合征介入术前应用他汀药物强化治疗的临床观察

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摘要 目的观察急性冠状动脉综合征患者实施介入手术治疗前应用他汀药物强化治疗的临床效果。方法 80例急性冠状动脉综合征患者随机分为观察组和对照组,每组40例。观察组患者术前应用他汀药物,对照组患者术前不应用他汀药物,观察两组患者术前、术后的临床情况,术后心脏不良事件发生率及不良反应情况。结果他汀药物强化治疗前,两组患者临床症状比较差异无统计学意义(P>0.05),应用他汀药物的观察组术前和术后的血脂水平、血清C反应蛋白(CRP)水平、血清肌钙蛋白I(c Tn I)和肌酸激酶同工酶水平(CK-MB)水平明显低于对照组,术后心脏不良事件发生率低于对照组,差异具有统计学意义(P<0.05),虽然术后出现一些药物不良反应,但不严重。结论急性冠状动脉综合征患者介入手术前应用他汀药物强化治疗效果确切,不良反应小,安全可靠,值得临床应用推广。
作者 罗进光
出处 《中国实用医药》 2015年第18期158-159,共2页 China Practical Medicine
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