调Q开关紫翠宝石激光治疗脂溢性角化病临床疗效观察及其生活质量评析

Observation of Clinical Effect of Q-switched Alexandrite Laser on Treatment and Analysis of Quality of Life of Seborrheic Keratosis

目的:观察调Q开关紫翠宝石激光治疗脂溢性角化病的临床疗效及评价其治疗前后的生活质量之变化。方法:利用调Q开关紫翠宝石激光治疗81例脂溢性角化病患者,根据皮损部位、性质选用不同的能量治疗且治疗前后通过问卷调查的形式了解患者术前的一般状况及治疗前后其生活质量的改变情况。结果:治疗1,2,3次的痊愈率分别为47.83%,85.71%,100%,而有效率分别为94.20%,100%,100%,显示治疗次数愈多,效果愈好。患者满意度为96.30%,医生满意度为92.60%;术前与术后DLQI总分P值<0.01,有显著统计学意义,提示治疗后总体生活质量获得提升。结论:调Q开关紫翠宝石激光治疗脂溢性角化病安全、有效,且可提升患者生活质量,值得推广。

Objective：To observe clinical effect on 81 patients with seborrheic keratosis treated by Q-switched Alexandrite laser and to analyze the influence on the quality of their life before and after the treatment through the questionnaire survey. Method：Treat 81 patients with seborrheic keratosis by Q-switched Alexandrite laser with different energy parameters according to the region and nature of skin lesions,besides,assess the quality of patients＇ life before and after the treatment through the questionnaire survey,dermatology life quality index（DLQI）. Results：After 1st,2nd and 3rd therapy,the cure rate were respectively 47.83%,85.71%,100%; the efficiency rate were respectively 94.20%,100%,100%,it shows that the effect of treatment increases as the number of times increases. The satisfaction index of patients was 96.30%,and the satisfaction index of doctors was 92.60%.The P value of total score of DLQI before and after the treatment was less than 0.01,it shows that the therapy can promote the quality of patients＇ life. Conclusion：Q-switched Alexandrite laser is not only safe but also valid for the treatment of seborrheic keratosis,and it canimprove the quality of patients＇ life,therefore,it＇s worth widely applying.