电子支气管镜检查对艾滋病并肺结核的临床意义研究

Clinical Significance of the Electronic Bronchoscopy for AIDS Complicated by Pneumonophthisis

目的探讨经电子支气管镜刷检、灌洗及培养对艾滋病并肺结核检查准确率、临床意义及价值.方法对2012年12月至2014年12月诊断艾滋病并肺结核110例行电子支气管镜肺泡灌洗(BALF)、刷检及结核分枝杆菌(MTB)培养,同时行痰查MTB、痰MTB培养、结核抗体、T细胞斑点实验(T SPOT-TB)、结核菌素(PPD)实验等结核专项检查,对相关检验结果进行对比研究分析.结果 110例艾滋病并肺结核患者痰查MTB及痰MTB培养阳性率、T SPOT-TB阳性率为2.7%、4.5%、13.6%、结核抗体阳性率10.9%,PPD试验阳性率8.1%,支气管镜检查刷检及BALF涂片及培养结果阳性率为22.5%、24.5%、30.9%,两两对照比较具有统计学意义(P<0.05).结论支气管镜检查对艾滋病并肺结核患者相比常规痰查MTB、痰MTB培养检查,其检查结果更准确,具有较高临床意义及应用价值.

Objective To investigate the accurate rate, clinical significance and value of bronchial brushing,bronchoalveolar lavage and culture through electronic bronchoscopy in detection of AIDS complicated by pneumonophthisis.Methods From December 2012 to December 2014,110 AIDS complicated by pneumonophthisis patients received bronchial brushing, bronchoalveolar lavage and MTB culture through electronic bronchoscopy,and also given sputum MTB test,sputum MTB culture,TB antibody,T SPOT- TB and PPD test,and the test results were analyzed.Result The positive rate of sputum MTB test,sputum MTB culture and T SPOT- TB was 2.7%,4.5% and 13.6%,respectively.The positive rate of TB antibody,and PPD test was 10.9% and 8.1%,respectively.The positive rate of electronic bronchoscopy and bronchoalveolar lavage fluid and TB culture was 22.5%,24.5%and 30.9%,respectively.Conclusion The electronic bronchoscopy is more accurate than sputum MTB test and MTB culture in detection of detection of AIDS complicated by pneumonophthisis,so it has good clinical significance and value.