期刊文献+

血清miRNA对中医辨证论治的指导意义 被引量:5

下载PDF
导出
摘要 目的:探讨血清miRNA对中医辨证论治的指导意义。方法:分析血清miRNA及中医证的特点,miRNA表达的时序性和特异性与证候的动态变化非常相似,将血清miRNA引入中医药辨证论值得研究领域关注,从而阐明中医证候的实质及科学内涵。结论:血清miRNA可以作为微观辨证的指标与宏观辨证相结合提高辩证的准确性,也可为临床个体化治疗提供重要的指导作用。
出处 《陕西中医》 2015年第7期891-893,共3页 Shaanxi Journal of Traditional Chinese Medicine
基金 广东省财政厅课题[粤财工(2013)] 广东省中医药管理局课题(20142066) 广东省中医药强省建设专项中医优势病种突破项目[粤财社(2014953)]
  • 相关文献

参考文献9

  • 1Zen K,Zhang CY.Circulating microRNAs:a novel class of biomarkers to diagnose and monitor human cancers[J].Med Res Rev,2012,32:326-348.
  • 2李洁,秦性良,邵宁生.MicroRNA及其靶基因的时空特异性与动态变化[J].生物化学与生物物理进展,2013,40(7):617-626. 被引量:16
  • 3Hui Zhang,Yan Guan,Yi-Yu Lu,et al.circulating mir-583and mir-663refer to zheng differentiation in chronic hepatitis B[J].Evidence-Based Complementary and Alternative Medicine Volume,2013:751341.
  • 4Chen QL,Lu YY,Zhang GB,et al.Characteristic Analysis from Excessive to Deficient Syndromes in Hepatocarcinoma Underlying miRNA Array Data[J].Evid Based Complement Alternat Med,2013:1-8.
  • 5冯知涛,李娟,任洁.类风湿关节炎患者外周血miR-146a、miR-16的表达水平及临床指标与中医证型的关系探讨[J].热带医学杂志,2011,11(11):1226-1229. 被引量:14
  • 6Gao S,Chen LY,Wang P,et al.MicroRNA Expression in Salivary Supernatant of Patients with Pancreatic Cancer and Its Relationship with ZHENG[J].Biomed Res Int,2014:1-8.
  • 7李立平,吴炜景,邱娴,李晓,赵亚刚.广东地区胃癌患者中医临床证候分型与miR-449表达相关性研究[J].中华中医药学刊,2013,31(12):2695-2698. 被引量:4
  • 8Jiang C,Liu P,Zhang J,et al.Clinical Study of Effects of Jian Ji Ning,a Chinese Herbal Medicine Compound Preparation,in Treating Patients with Myasthenia Gravis via the Regulation of Differential MicroRNAs Expression in Serum[J].Evidence-Based Complementary and Alternative Medicine,2014:1-14.
  • 9Wang K,Zhang S,Marzolf B,et al.Circulating microRNAs,potentional biomarkers for drug-induced liver injury.[J] Proc Natl Acad Sci U S A,2009,106(11):4402-7.

二级参考文献23

  • 1黄李平,吕军影,何源浩,王立群.类风湿性关节炎中医证型与免疫指标变化关系探讨[J].实用中西医结合临床,2002,2(3):3-4. 被引量:19
  • 2吕诚,肖诚,赵林华,查青林,闫小萍,王建明,张英泽,周扬文,徐世杰,李梢,吕爱平.寒热证候类风湿性关节炎患者外周血CD_4^+T淋巴细胞基因表达谱初步探索[J].中国中医基础医学杂志,2006,12(2):130-133. 被引量:24
  • 3Bushati N, Cohen SM. microRNA functions [J]. Annu Rev Cell Dev Biol, 2007,23 ( 1 ) : 175-205.
  • 4Pauley KM,Satoh M,Chan AL,et al.Upregulated miR-146a expression in peripheral blood mononuclear cells from cells from rheumatoid arthritis patient [J].Arthritis Res Ther, 2008,10 (4) : R101.
  • 5Jing Q, Huang S, Guth S, et al.Involvement of microRNA in AU- rich element-mediated mRNA instability [ J ]. Cell, 2005,120 (5) : 623-634.
  • 6孙荣武,王鸿利.临床免疫学[M].上海:上海科技出版社,2001.
  • 7Scott DL.Prognostic factors in early rheumatoid arthritis [J]. Rheumatology (Oxford), 2000,39 Suppl 1 : 24-29.
  • 8Muroi K,Amemiya Y,Sievers EL,et al.Expression of sialosyl-T and disialosyl-T antigens in erythroid cells[J].Leuk Lymphoma, 1997,25 (5-6) :403-414.
  • 9Visser H, le Cessie S, Vos K, et al.How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis [ J ]. Arthritis Rheum, 2002,46 (2) : 357-365.
  • 10Carpenter BW.Lymphoma of the appendix[J].Gastroin-test Radiol,1991,16(3):256-258.

共引文献31

同被引文献55

引证文献5

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部