新疆昌吉州99150例围产儿出生缺陷监测结果分析

Monitoring and analysis of 99150 perineonate birth defects

目的分析围产儿出生缺陷情况,了解其动态变化,进一步做好出生缺陷防控工作。方法对昌吉州2005年-2013年监测医院出生的孕28周至生后7天的围产儿按照国家出生缺陷监测方案进行监测。结果共监测99 150例围产儿,缺陷儿733例,出生缺陷总发生率为73.92/万,出生缺陷在2010年呈现高峰,2005年-2010年呈上升趋势,2011年-2013年逐年下降。主要缺陷类型是总唇裂、多指（趾）、神经管缺陷、先天性心脏病、马蹄足内翻。结论 2005年-2013年昌吉州围产儿出生缺陷发生率处较高水平,提示应深入研究出生缺陷致畸因素,普及健康教育,加强三级预防措施,降低出生缺陷发生水平,做好优生优育工作。

Objective：By analyzing 99 150 cases of perinatal birth defects,to understood the dynamic changes of the birth defects in Chang Ji region from 2005 to 2013,and a better job of birth defects prevention and control work should be done. Method：According to hospital-based monitory,perinatal infants aged from 28 weeks of gestation to 7 days after birth in Chang Ji region from 2005 to 2013 were monitored for birth defects. Results：A total of 99 150 cases of perinatal were monitored,733 were found defects in children,the incidence of birth defects was 73.92/10^4. Birth defects presents the peak in 2010,was established in 2005-2010 rise,declined year by year from 2011 to 2013. The main type of defect were congenital heart disease,total cleft lip,polydactyly,congenital hydrocephalus,neural tube defects. Conclusion：In Chang Ji region the incidence of perinatal birth defects course from 2005 to 2013 was at a high level,the factors of birth defects and universal access to health education should be studied to reduce the level of incidence of birth defects,prenatal and postnatal care work. Three-level prevention system are effective preventions of birth defects.