摘要
目的了解健康男性青年人群血清中人绒毛膜促性腺激素(HCG)水平的分布情况,为应征入伍新兵体检筛查HCG相关疾病,制订相应体检标准提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对该部近8年来自16个省市的364名入伍新兵进行了血清HCG水平检测和统计分析。结果结果发现新兵人群中存在HCG阳性者,8年间各年阳性检出率差异无统计学意义,阳性率范围在0.00%-6.82%,平均阳性率为4.67%;各省市及内陆与沿海地区间阳性检测率变化不明显,其中内蒙古(13.04%)、福建省(9.09%)、广西省(8.70%)和四川省(8.70%)阳性率较高,其余各省相对较低,而山东省、广东省、黑龙江和甘肃省未检出;入伍前工作与否,抗体阳性检出率差异无统计学意义。结论健康男性新兵人群血清中存在HCG阳性现象,其临床意义有待进一步研究探讨。
[ Objective ] To monitor the level of human chorionic gonadotropin (HCG) in healthy young male, and provide scientific evidence for setting up standard to screen HCG related disease among the military recruits. [ Methods ] Epidemiological survey was carried out using the enzyme-linked immunosorbent assay (ELISA) to test the serological level of HCG in 364 recruits from 16 provinces in the past 8 years, and the results were analyzed statistically. [ Results ] HCG positive individuals had been identified amongst the recruits. The positive rate showed no significant change yearly in the past 8 years, which ranged from 0.00% to 6.82% with the average of 4.67%. There was no sharp change of the positive rate amongst different provinces or between the coast and inland areas. The positive rates were higher in Inner Mongolia (13.04%), Fujian (9.09%), Guangxi (8.70%) and Sichuan (8.70%), and relatively low in the rest provinces. Negative results were observed in Shandong, Guangdong, Heilongjiang and Gansu. Employment status prior to recruitment had no correlation with HCG positive rate. [ Conclusions ] HCG positive cases are observed in healthy male recruits. The clinical importance of this observation remains to be clarified by further investigation.
出处
《中国现代医学杂志》
CAS
北大核心
2015年第19期51-54,共4页
China Journal of Modern Medicine
基金
全军医学科学技术研究"十二五"课题(No:CWS11L200)