青年与老年肺癌的临床及CT对比分析

CLINICAL AND CT MANIFESTATIONS OF LUNG CANCER IN YOUNG AND ELDERLY PATIENTS

目的探讨青年和老年肺癌临床及CT影像学特点的差异。方法采用回顾性分析的方法,收集经病理确诊的青年肺癌病人（≤40岁）102例、老年肺癌病人（≥60岁）108例,对比两组临床及影像学资料。结果青年组女性病人所占比例显著高于老年组（χ^2=7.68,P〈0.01）。青年组病理类型以腺癌为主,其次为小细胞癌;老年组以鳞癌为主,其次为腺癌（χ^2=13.73、11.00,P〈0.01）。MSCT影像学特点比较,青年组以周围型肺癌多见,其发生纵隔肺门淋巴结大、肺内及肺外转移的比例明显高于老年组（χ^2=4.23~47.19,P〈0.05）;老年组以中央型肺癌多见,其比例明显高于青年组（χ^2=41.74,P〈0.01）;两组中央型和周围型肺癌的CT征象差异无统计学意义（P〉0.05）。结论青年肺癌女性病人所占比例较高,病理以腺癌为主,CT征象以周围型肺癌多见,易发生纵隔肺门淋巴结大、肺内及远处转移。

Objective To explore the differences of clinical and CT imaging features between young and elderly patients with lung cancer. Methods Retrospective analysis was carried out for clinical data of lung cancer in 102 young patients（≤40years old）and 108 elderly patients（≥60years old）,their clinical and CT characteristics were compared and analyzed. Results In the young-patient group,the percentage of lung cancer in female patients was much higher than that in the elderly group（χ^2=7.68,P〈0.01）.As for pathology,in the young-patient group,mainly with adenoarcinoma,followed by small cell cancer;in the elderly-patient group,mainly with squamous carcinoma,followed by adenoarcinoma（χ^2=13.73,11.00;P〈0.01）.A comparison of imaging features between the two groups showed that：in the young group,peripheral lung cancer was mostly seen,the percentage of mediastinum-hilum lymphadenectasis,intrapulmonary and extrapulmonary metastasis was higher than that in the elderly group（χ^2=4.23-47.19,P〈0.05）;in the elderly group,central type lung cancer was more commonly seen,the percentage being higher than the young ones（χ^2=41.74,P〉0.01）.The differences of CT signs of central and peripheral lung cancer between the two groups were not statistically significant. Conclusion A higher percentage of lung cancer was noted in young women,mainly with adenocarcinoma.CT signs show mostly peripheral type,which is easy to cause mediastinum-hilum lymphadenectasis,intrapulmonary and distant metastasis.