神经外科院内获得性细菌性脑膜炎的治疗进展

Treatment progress of nosocomial bacterial meningitis in neurosurgery

院内获得性细菌性脑膜炎是一类严重的院内感染，具有高死亡率和致残率的特点。神经外科术后患者是院内获得性细菌性脑膜炎的高危人群，这一院内感染使得患者住院时间和医疗费用显著增加。本文回顾了近年来神经外科患者院内获得性细菌性脑膜炎的病因、治疗方案和研究进展，提出了尚未解决的问题和今后的研究方向。

With high morbidity and mortality,nosocomial bacterial meningitis（NBM）is a kind of serious nosocomial infection.Post-neurosurgical patients are at a high risk of this infection andNBM in-creases hospital stay and medical expense obviously.In this article,we reviewed recent studiesonpathogen-esis,treatment,and research progress of NBM in neurosurgical patients,and presented unresolved ques-tions and research direction in the future.