摘要
目的研究化生平胶囊对胃溃疡大鼠模型的治疗作用。方法采用盐酸-乙醇法制造大鼠胃溃疡模型,研究化生平胶囊对其溃疡指数、溃疡抑制率、血清及胃组织NO含量的影响,并通过光镜和电镜观察各组大鼠胃黏膜的病理变化。结果化生平胶囊可降低胃溃疡大鼠溃疡指数、提高抑制率,提高血清及组织中NO含量;光镜和电镜结果显示,化生平胶囊可明显改善大鼠胃组织的溃疡变化。结论化生平胶囊对大鼠胃溃疡有明显的保护作用。
Objective To study the effect of Huashengping Capsules on gastric ulcer rats.Method Hydrochloric acid and alcohol were used to make gastric ulcer model on rats and the content of Huashengping Capsules was administrated.The ulcer index,inhibiting rate of astric ulcer,NO concentration in serum and stomach,and the histological change on electron microscope were observed.Results Huashengping Capsules decreased the ulcer index and NO content in serum and stomach,meanwhile increased the inhibiting rate of astric ulcer.Histological ulcer was improved by Huashengping Capsules.Conclusion Huashengping Capsules have protective effect on gastric ulcer rats.
出处
《西北药学杂志》
CAS
2015年第4期373-376,共4页
Northwest Pharmaceutical Journal
基金
陕西省中医药管理局基金(ZY28)
关键词
化生平胶囊
胃溃疡
胃黏膜
NO
Huashengping Capsules
gastric ulcer
gastric mucosa
NO
