我院2012-2014年门诊降糖药类基本药物使用情况分析

Utilization Analysis of Antidiabetic Essential Medicines in the Outpatient of Our Hospital from 2012 to 2014

目的:为促进降糖药类基本药物在临床的合理使用提供参考。方法:采用回顾性分析方法,对2012年5月1日-2014年4月30日我院门诊降糖药的销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计并排序、分析。结果:胰岛素和口服降糖药的销售金额及DDDs都呈上升趋势。口服降糖药中销售金额及DDDs排前3位的是阿卡波糖、二甲双胍和格列美脲,胰岛素中DDDs最高的是短效和预混重组人胰岛素,均为2012年版《国家基本药物目录》品种;其余基本药物格列本脲片、格列吡嗪片及中成药DDDs均较小;长效胰岛素类似物DDC明显高于其余种类胰岛素。2012年版《国家基本药物目录》实施后降糖药类基本药物销售比例由10.48%增长到67.78%。结论:我院门诊降糖药物使用基本合理,阿卡波糖和二甲双胍用量最大,胰岛素类似物DDDs增长迅速。

OBJECTIVE：To provide reference for clinical rational use of antidiabetic essential medicines. METHODS：Retrospective analysis was used to sort and analyze the consumption sum,DDDs and DDC of antidiabetic drugs in the outpatient of our hospital from May 1st,2012 to Apr. 30 th,2014. RESULTS：The consumption sum and DDDs of insulin and oral antidiabetic drugs had upward trend. The top 3 consumption sum and DDDs of oral antidiabetic drugs were acarbose,metformin and glimepiride,and the highest DDDs of insulin was short-acting and premixed recombinant human insulin,all of them were in the National Essential Medicine List（2012 edition）;DDDs of Glibenclamide tablets,Glipizide tablets and Chinese patent medicine were relatively small;DDC in long-acting insulin analogues was obviously higher than other kinds of insulin. The sales ratio of essential medicines was increased from 10.48% to 67.78% after National Essential Medicine List（2012 edition）carried out. CONCLUSIONS：The use of antidiabetic drugs in the outpatient of our hospital is basically rational. Acarbose and metformin have the highest DDDs,and DDDs of insulin analogues grow rapidly.