大腹皮气相色谱指纹图谱质量控制研究

Research on the Quality Control in Fingerprint of Areca Peel by Gas Chromatography

目的:建立大腹皮石油醚部位气相色谱(GC)指纹图谱分析方法,为其质量评价提供依据。方法:采用GC法建立10批不同产地大腹皮石油醚部位的指纹图谱,并对指纹图谱数据进行聚类分析和相似度分析,研究大腹皮的GC指纹图谱的相似性。结果:建立了大腹皮的GC指纹图谱,标定了8个共有特征峰。各产地药材均有上述特征,但特征峰的相对峰面积存在一定差异。结论:GC指纹图谱分析法有良好的重现性和精密度,可作为大腹皮药材的质量控制方法。

OBJECTIVE：To establish the gas chromatography（GC）fingerprint for the petroleum ether part of Areca peel and provide reference for the quality evaluation. METHODS：GC was conducted to establish the fingerprint for the petroleum ether part of Areca peel from 10 different areas,the cluster analysis and similarity of fingerprint data were conducted to study the similarity of GC fingerprint of Areca peel. RESULTS：There were totally 8 common peaks. All the medicine materials had the characteristics,but there were differences among the relative peak area. CONCLUSIONS：The GC fingerprint has high importance and precision and can be used for the quality control of Areca peel.