某基层医院特殊级抗菌药物临床会诊回顾分析

Retrospective Analysis of Clinical Consultations for Special Class Antibacterial Drugs in a Primary Hospital

目的评估基层医院特殊级抗菌药物临床使用管理的效果。方法收集医院特殊级抗菌药物会诊记录,对32例患者年龄、感染疾病分布、病原学、疗效、抗菌药物选择等进行分析。结果 50岁以上占84.38%,下呼吸道感染占78.13%,呼吸科和重症监护室(ICU)占68.75%,平均使用疗程6.45 d,细菌学疗效清除率37.04%,临床疗效有效率68.75%,特殊级抗菌药物使用有效干预率34.38%。结论医生多关注临床疗效,对细菌学疗效重视不够。临床药师可利用专业特长,参与特殊级抗菌药物会诊,优化抗感染治疗方案,减少药品不良反应及细菌耐药性产生,促进特殊级抗菌药物的合理使用。

Objective To evaluate the effects of clinical use management of special class antibacterial drugs in a primary hospital. Methods The consultation records of special class antibacterial drugs in a hospital were collected. Totally 32 cases were analyzed on the age,infected disease distribution,etiology,curative efficacy and the selections of antibacterial drugs. Results The cases aged over50 years old accounted for 84. 38%; the lower respiratory tract infection accounted for 78. 13%; the respiratory department and ICU accounted for 68. 75 %; the average course of treatment was 6. 45 d; in bacteriological efficacy,the clearance rate was 37. 04%; the clinical effective rate was 68. 75%; the effective intervention rate of special class antibacterial drugs was 34. 38%. Conclusion Doctor paying attention to the curative effect and bacteriological efficacy are insufficient. Clinical pharmacists can use their specialty advantages to participate in the consultation of special class antibacterial drugs,optimize the anti- infection therapeutic regimen,reduce the occurrence of adverse drug reactions and bacterial drug resistance and promote the rational use of special class antibacterial drugs.