ABCDE镇静镇痛集束预防ICU机械通气患者谵妄和乏力的研究进展

The research progress on using ABCDE sedatives and analgesics bundle to prevent delirium and fatigue in mechanical ventilation patients in ICU

ICU获得性谵妄和乏力在重症监护室(ICU)有较高的发生率,其发生会延长患者机械通气时间及住院时间,增加患者死亡风险,遗留较长时间的认知障碍或功能受损。预防ICU患者谵妄和乏力发生是提高护理质量的关键。ICU获得性谵妄和乏力的发生一般是多因素作用的结果,很难通过单一的措施进行很好的预防。ABCDE镇静镇痛集束是基于证据的预防谵妄和ICU获得性谵妄的综合措施。本文就ABCDE镇静镇痛集束进行综述,介绍该集束实施方法、安全性及在应用中存在的问题,以供临床参考。

Delirium and ICU-acquired weakness fatigue have high incidence in ICU. Delirium and ICU-acquired fatigue will prolong mechanical ventilation and hospital stay, increase mortality, and cause cognitive disorder and lose of function. Preventing delirium and ICU-acquired fatigue is key for quality of nursing care. Any single measure alone is difficult for preventing delirium and ICU-acquired fatigue due to it＇s complexities＇. The ABCDE sedatives and analgesics bundle is an evidence-based and multidisciplinary strategy to reduce sedative exposure, promote liberation from mechanical ventilation, and improve post-ICU cognitive function and functionality.The purpose of this article is explore the ABCDE bundle for management the sedatives and analgesics.