宿主菌抗噬菌体机制的研究进展

Advances of Researches on Anti-phage Mechanisms of Host

噬菌体又称细菌病毒,是公认最丰富的微生物,也是最多样性的,这种多样性是适应所面对选择性压力例如普遍存在宿主菌的噬菌体抗性机制。噬菌体通过6步(吸附、注入、复制、转录翻译、组装和释放)侵入细菌并使之裂解,但是当噬菌体感染细菌,就会面临细菌抗噬菌体的机制,宿主菌能够进化出多种抗噬菌体的机制来避免噬菌体的侵染和裂解。本文就对宿主菌抗噬菌体各种机制作一综述。

Phages also known as bacteria viruses,are recognized as the most abundant and diverse microbes.This diversity is adapting to the selective pressures such as the prevalence of the phage resistance mechanisms of bacteria.Phages invade and lyse bacterial through six steps（adsorption,injection,replication,transcription translation,assemble,release）.Bacteria evolve to many anti-phage mechanisms to avoid phage infection and lysis.This paper focus on a variety of anti-phage mechanisms of bacteria.